M Moldovan相关文献与解析，生知库 | 链接生命科学的每一步

Genome-wide CRISPR screens identify the EXO1-CAF-1 pathway suppressing R-loop-associated DNA damage.

全基因组 CRISPR 筛选发现 EXO1-CAF-1 通路可抑制 R 环相关的 DNA 损伤。

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkag226

Nusawardhana Alexandra, Hale Anastasia, Straka Joshua, Nicolae Claudia M, Moldovan George-Lucian

The RRM domains of PARP14 mediate replication fork degradation in BRCA2-deficient cells.

PARP14 的 RRM 结构域介导 BRCA2 缺陷细胞中的复制叉降解。

期刊:NAR Cancer

影响因子:3.2

doi:10.1093/narcan/zcag005

Hale Anastasia, Lynch Katie A, Dhoonmoon Ashna, Nicolae Claudia M, Moldovan George-Lucian

Genome-wide CRISPR screens identify DNA repair and R-loop suppression as regulators of the cellular sensitivity to environmentally relevant Bisphenol A exposure

全基因组 CRISPR 筛选发现 DNA 修复和 R 环抑制是细胞对环境相关双酚 A 暴露敏感性的调节因子

期刊:

影响因子:

doi:10.64898/2026.04.13.718249

Hale, Anastasia; Nusawardhana, Alexandra; Straka, Joshua; Nicolae, Claudia M; Moldovan, George-Lucian

细胞生物学

发表日期：2026

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Role of Translesion DNA Synthesis in the Metabolism of Replication-associated Nascent Strand Gaps

跨损伤DNA合成在复制相关新生链缺口代谢中的作用

期刊:Journal of Molecular Biology

影响因子:4.5

doi:10.1016/j.jmb.2023.168275

Khatib, Jude B; Nicolae, Claudia M; Moldovan, George-Lucian

代谢

发表日期：2024

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Mechanisms of PARP1 inhibitor resistance and their implications for cancer treatment

PARP1抑制剂耐药机制及其对癌症治疗的影响

期刊:NAR Cancer

影响因子:3.2

doi:10.1093/narcan/zcac042

Jackson, Lindsey M; Moldovan, George-Lucian

CRISPR screens guide the way for PARP and ATR inhibitor biomarker discovery

CRISPR筛选为PARP和ATR抑制剂生物标志物的发现指明了方向。

期刊:

影响因子:

doi:10.1111/febs.16217

Schleicher, Emily M; Moldovan, George-Lucian

Shorter axon initial segments do not cause repetitive firing impairments in the adult presymptomatic G127X SOD-1 Amyotrophic Lateral Sclerosis mouse

较短的轴突起始节段不会引起成年无症状 G127X SOD-1 肌萎缩侧索硬化症小鼠的重复性放电障碍

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-019-57314-w

V S Bonnevie #, K P Dimintiyanova #, A Hedegaard, J Lehnhoff, L Grøndahl, M Moldovan, C F Meehan

Sex Differences in Quality of Life in Patients With Systemic Lupus Erythematosus

系统性红斑狼疮患者生活质量的性别差异

期刊:Arthritis Care & Research

影响因子:3.3

doi:10.1002/acr.23588

Jolly, Meenakshi; Sequeira, Winston; Block, Joel A; Toloza, Sergio; Bertoli, Ana; Blazevic, Ivanna; Vila, Luis M; Moldovan, Ioana; Torralba, Karina D; Mazzoni, Davide; Cicognani, Elvira; Hasni, Sarfaraz; Goker, Berna; Haznedaroglu, Seminur; Bourre-Tessier, Josiane; Navarra, Sandra V; Mok, Chi Chiu; Weisman, Michael; Clarke, Ann E; Wallace, Daniel; Alarcón, Graciela

Drivers of Satisfaction With Care for Patients With Lupus

影响狼疮患者对护理满意度的因素

期刊:ACR Open Rheumatology

影响因子:2.8

doi:10.1002/acr2.11085

Jolly, Meenakshi; Sethi, Bhavika; O'Brien, Courtney; Sequeira, Winston; Block, Joel A; Toloza, Sergio; Bertoli, Ana; Blazevic, Ivana; Vilá, Luis M; Moldovan, Ioana; Torralba, Karina D; Cicognani, Elvira; Mazzoni, Davide; Hasni, Sarfaraz; Goker, Berna; Haznedaroglu, Seminur; Bourre-Tessier, Josiane; Navarra, Sandra V; Mok, Chi Chiu; Clarke, Ann; Weisman, Michael; Wallace, Daniel

发表日期：2019

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The nuclease EXO1 promotes genomic instability by degrading nascent DNA in BRCA-proficient cells.

核酸酶 EXO1 通过降解 BRCA 功能正常细胞中的新生 DNA 来促进基因组不稳定。

Genome-wide CRISPR screens identify the EXO1-CAF-1 pathway suppressing R-loop-associated DNA damage.

全基因组 CRISPR 筛选发现 EXO1-CAF-1 通路可抑制 R 环相关的 DNA 损伤。

The RRM domains of PARP14 mediate replication fork degradation in BRCA2-deficient cells.

PARP14 的 RRM 结构域介导 BRCA2 缺陷细胞中的复制叉降解。

Genome-wide CRISPR screens identify DNA repair and R-loop suppression as regulators of the cellular sensitivity to environmentally relevant Bisphenol A exposure

全基因组 CRISPR 筛选发现 DNA 修复和 R 环抑制是细胞对环境相关双酚 A 暴露敏感性的调节因子

Role of Translesion DNA Synthesis in the Metabolism of Replication-associated Nascent Strand Gaps

跨损伤DNA合成在复制相关新生链缺口代谢中的作用

Mechanisms of PARP1 inhibitor resistance and their implications for cancer treatment

PARP1抑制剂耐药机制及其对癌症治疗的影响

CRISPR screens guide the way for PARP and ATR inhibitor biomarker discovery

CRISPR筛选为PARP和ATR抑制剂生物标志物的发现指明了方向。

Shorter axon initial segments do not cause repetitive firing impairments in the adult presymptomatic G127X SOD-1 Amyotrophic Lateral Sclerosis mouse

较短的轴突起始节段不会引起成年无症状 G127X SOD-1 肌萎缩侧索硬化症小鼠的重复性放电障碍

Sex Differences in Quality of Life in Patients With Systemic Lupus Erythematosus

系统性红斑狼疮患者生活质量的性别差异

Drivers of Satisfaction With Care for Patients With Lupus

影响狼疮患者对护理满意度的因素