Phase 1/1b dose escalation and expansion study of BEZ235, a dual PI3K/mTOR inhibitor, in patients with advanced solid tumors including patients with advanced breast cancer
BEZ235(一种双重PI3K/mTOR抑制剂)在晚期实体瘤患者(包括晚期乳腺癌患者)中的1/1b期剂量递增和扩展研究
期刊:Cancer Chemotherapy and Pharmacology
影响因子:2.3
doi:10.1007/s00280-018-3610-z
Rodon, Jordi; Pérez-Fidalgo, Alejandro; Krop, Ian E; Burris, Howard; Guerrero-Zotano, Angel; Britten, Carolyn D; Becerra, Carlos; Schellens, Jan; Richards, Donald A; Schuler, Martin; Abu-Khalaf, Maysa; Johnson, Faye M; Ranson, Malcolm; Edenfield, Jeff; Silva, Antonio P; Hackl, Wolfgang; Quadt, Cornelia; Demanse, David; Duval, Vincent; Baselga, Jose