日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The development of a hiPSC-based platform to identify tissue-dependencies of IDH1 R132H

开发基于 hiPSC 的平台来识别 IDH1 R132H 的组织依赖性

N Z Mehjardi, J Kessler, A Y Sanin, D Picard, P Westhoff, Ann-Christin Nickel, C Uhlmann, W Shi, H J Steiger, M Remke, I Fischer, D Vordermark, R S Croner, U D Kahlert

A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma

纤毛处的区域化磷酸肌醇信号轴受 INPP5E 调控,以维持纤毛并促进 Sonic Hedgehog 髓母细胞瘤

S E Conduit, V Ramaswamy, M Remke, D N Watkins, B J Wainwright, M D Taylor, C A Mitchell, J M Dyson

CBF1 is clinically prognostic and serves as a target to block cellular invasion and chemoresistance of EMT-like glioblastoma cells

CBF1 具有临床预后作用,可作为阻断 EMT 样胶质母细胞瘤细胞侵袭和化学耐药性的靶点

D Maciaczyk, D Picard, L Zhao, K Koch, D Herrera-Rios, G Li, V Marquardt, D Pauck, T Hoerbelt, W Zhang, D M Ouwens, M Remke, T Jiang, H J Steiger, J Maciaczyk, U D Kahlert

PDTM-46. TARGETING METABOLIC ADAPTATION IN MYC DRIVEN PEDIATRIC NEURONAL TUMORS

PDTM-46. 靶向MYC驱动的儿童神经肿瘤的代谢适应

Tseng, Ta-Feng; Yang, Yang-Li; Lin, Yuh-Jiuan; Lou, Shyh-Liang; Delaidelli, Alberto; Negri, Gian Luca; Jan, Asad; Jansonius, Brandon; Lim, Jonathan K M; Leprivier, Gabriel; Kool, Marcel; Pfister, Stefan M; Remke, Marc; Taylor, Michael; Maris, John M; Sorensen, Poul H

WIP1 modulates responsiveness to Sonic Hedgehog signaling in neuronal precursor cells and medulloblastoma

WIP1 调节神经元前体细胞和髓母细胞瘤对 Sonic Hedgehog 信号的响应

J Wen, J Lee, A Malhotra, R Nahta, A R Arnold, M C Buss, B D Brown, C Maier, A M Kenney, M Remke, V Ramaswamy, M D Taylor, R C Castellino

YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells

YB-1 在髓母细胞瘤中升高,并促进 Sonic Hedgehog 依赖性小脑颗粒神经元祖细胞和髓母细胞瘤细胞的增殖

A Dey, M Robitaille, M Remke, C Maier, A Malhotra, A Gregorieff, J L Wrana, M D Taylor, S Angers, A M Kenney

The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variants

WIP1癌基因促进侵袭性髓母细胞瘤变异株的进展和侵袭。

M C Buss ,M Remke ,J Lee ,K Gandhi ,M J Schniederjan ,M Kool ,P A Northcott ,S M Pfister ,M D Taylor ,R C Castellino

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

表观基因组学改变定义致命的 CIMP 阳性婴儿室管膜瘤

S C Mack, H Witt, R M Piro, L Gu, S Zuyderduyn, A M Stütz, X Wang, M Gallo, L Garzia, K Zayne, X Zhang, V Ramaswamy, N Jäger, D T W Jones, M Sill, T J Pugh, M Ryzhova, K M Wani, D J H Shih, R Head, M Remke, S D Bailey, T Zichner, C C Faria, M Barszczyk, S Stark, H Seker-Cin, S Hutter, P Johann, S Be

Epigenetic silencing of miRNA-9 is associated with HES1 oncogenic activity and poor prognosis of medulloblastoma

miRNA-9 的表观遗传沉默与 HES1 致癌活性和髓母细胞瘤预后不良相关

G Fiaschetti, L Abela, N Nonoguchi, A M Dubuc, M Remke, A Boro, E Grunder, U Siler, H Ohgaki, M D Taylor, M Baumgartner, T Shalaby, M A Grotzer