Lumican is upregulated in osteoarthritis and contributes to TLR4-induced pro-inflammatory activation of cartilage degradation and macrophage polarization
Lumican 在骨关节炎中上调,并有助于 TLR4 诱导的软骨降解和巨噬细胞极化的促炎激活
期刊:Osteoarthritis and Cartilage
影响因子:7.2
doi:10.1016/j.joca.2019.10.011
G Barreto, B Senturk, L Colombo, O Brück, P Neidenbach, G Salzmann, M Zenobi-Wong, M Rottmar
免疫
细胞生物学
关节炎
巨噬细胞
Cell sorting
FCM