日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Changes in Clinician Time Expenditure and Visit Quantity With Adoption of Artificial Intelligence-Powered Scribes: A Multisite Study

采用人工智能辅助医疗记录员后,临床医生时间投入和就诊次数的变化:一项多中心研究

Rotenstein, Lisa S; Holmgren, A Jay; Thombley, Robert; Sriram, Aditi; Dbouk, Reema H; Jost, Melissa; Aizenberg, Debbie; MacDonald, Scott; Kanaparthy, Naga; Williams, Brian; Hsiao, Allen; Schwamm, Lee; Murray, Sara; Byron, Maria; You, Jacqueline G; Centi, Amanda J; Iannaccone, Christine; Frits, Michelle; Landman, Adam B; Singh, Karandeep; Tai-Seale, Ming; Cao, Jie; Lawrence, Katharine; Mann, Devin; Holland, Christopher; Blanchette, Bryan; Ehrenfeld, Jesse; Melnick, Edward R; Bates, David W; Adler-Milstein, Julia; Mishuris, Rebecca G

Epigenetic Regulation of Chromosomal Instability by EZH2 Methyltransferase.

EZH2甲基转移酶对染色体不稳定性进行表观遗传调控。

Bai Yang, Agustinus Albert S, Yomtoubian Shira, Meydan Cem, McNally Dylan R, Yoffe Liron, Hubisz Melissa J, Tranquille Marvel, Pramod Sneha, Hong Christy, Plasilova Magdalena L, Kapoor Aakanksha R, Singh Arshdeep, Withers Henry, Dow Lukas E, Laughney Ashley M, Bhinder Bhavneet, Elemento Olivier, Melnick Ari M, Bakhoum Samuel F, Mittal Vivek

T follicular helper cells transiently unlock a plasticity state in germinal centre B cells during the humoral immune response.

在体液免疫反应过程中,滤泡辅助性T细胞可短暂地激活生发中心B细胞的可塑性状态。

Scourzic Laurianne, Izzo Franco, Teater Matt, Polyzos Alexander P, Cucereavii Lucretia, Chin Christopher R, Papin Antonin, Pinto Hugo B, Mlynarczyk Coraline, Tsialta Ioanna, Xia Min, Lidoski Abigail, Myers Robert M, Israel Eva M, Venturutti Leandro, Mackay Simon P, Hoehn Kenneth B, Skoultchi Arthur I, Béguelin Wendy, Stadtfeld Matthias, Chen Zhengming, Landau Dan A, Melnick Ari M, Apostolou Effie

Tet2 deficiency promotes IgG1+ B-cell expansion and differentiation blockade through deregulation of the Nfkbia-c-Rel axis

Tet2 缺陷通过 Nfkbia-c-Rel 轴的失调促进 IgG1+ B 细胞扩增和分化阻滞

Ghamlouch, Hussein; Degaud, Michaël; Della-Valle, Veronique; Eeckhoutte, Alexandre; Armand, Marine; Joudat, Amina; Decaudin, Camille; Dominguez, Pilar M; Rosikiewicz, Wojciech; Pawlikowska, Patrycja; Darwiche, Walaa; Mouly, Enguerran; Li, Sheng; Melnick, Ari M; Aoufouchi, Said; Bernard, Olivier A

The hematopoietic stem cell MYB enhancer is essential for and recurrently amplified during T cell leukemogenesis

造血干细胞MYB增强子对于T细胞白血病的发生至关重要,并在T细胞白血病发生过程中反复扩增。

Mullin, Carea; Lin, Karena; Choe, Elizabeth; Sha, Cher; Shukla, Zeel; Campbell, Koral; McCarter, Anna C; Wang, Annie; Nieves-Salva, Jannaldo; Khan, Sarah; Keeley, Theresa M; Liang, Shannon; Wang, Qing; Melnick, Ashley F; Evans, Pearl; Monovich, Alexander C; Iyer, Ashwin; Kodgule, Rohan; Deng, Yamei; da Veiga Leprevost, Felipe; Barnett, Kelly R; Pölönen, Petri; Khoriaty, Rami; Savic, Daniel; Teachey, David T; Mullighan, Charles G; Cieslik, Marcin; Nesvizhskii, Alexey I; Samuelson, Linda C; Jones, Morgan; Li, Qing; Ryan, Russell Jh; Chiang, Mark Y

Epigenetic priming promotes tyrosine kinase inhibitor resistance and oncogene amplification

表观遗传启动促进酪氨酸激酶抑制剂耐药性和癌基因扩增

Rebecca M Starble #,Eric G Sun #,Rana Gbyli,Jonathan Radda,Jiuwei Lu,Tyler B Jensen,Ning Sun,Nelli Khudaverdyan,Ting Zhao,Bomiao Hu,Mary Ann Melnick,Shuai Zhao,Nitin Roper,Gang Greg Wang,Alan J Tackett,Yinsheng Wang,Jikui Song,Katerina Politi,Siyuan Wang,Andrew Z Xiao

Wild-type p53 overexpression in NPM1-mutated acute myeloid leukemia: potential implications for disease biology and therapy response

NPM1突变型急性髓系白血病中野生型p53的过表达:对疾病生物学和治疗反应的潜在影响

Barone, Paul D; Dzedzik, Siarhei; Kleinman, Ashley S; Chin, Christopher R; Meydan, Cem; Valencia, Itzel; Sugita, Mayumi; Guzman, Monica L; Fein, Joshua A; Kaner, Justin D; Desai, Pinkal; Roboz, Gail J; Melnick, Ari M; Mason, Christopher E; Patel, Sanjay S

CCAAT-enhancer binding protein delta functions as a tumor suppressor gene in acute myeloid leukemia

CCAAT增强子结合蛋白δ在急性髓系白血病中发挥抑癌基因的作用。

Prajapati, Subhash C; Meydan, Cem; Neelamraju, Yaseswini; Wang, Zhenjia; Atwood, Grant; Paudel, B Bishal; Fan, Hao; Dunham, Nicholas; Dillon, Richard; Gandara, Jorge A; Lee, Tak; Sheridan, Caroline; Wang, Shengyuan; Zumbo, Paul; Becker, Michael W; Bullinger, Lars; Carroll, Martin P; D'Andrea, Richard J; Levine, Ross L; Mason, Christopher E; Melnick, Ari M; Zang, Chongzhi; Bekiranov, Stefan; Garrett-Bakelman, Francine E

Exposure limits to radiofrequency EMF do not account for cancer risk or reproductive toxicity assessed from data in experimental animals

射频电磁场暴露限值并未考虑根据实验动物数据评估的癌症风险或生殖毒性。

Melnick, Ronald L; Moskowitz, Joel M

Large-scale functional assessment of variants of the potassium channel Kir2.1: Clinical and comparative insights

大规模钾通道 Kir2.1 变体的功能评估:临床和比较见解

Anderson, Corey L; Munuwar, Saba; Walters, Janay K; McWilliams, Seamus F; Melnick, Molly; Langer, Emma R; Bereslavskyy, Igor; Milaitis, Maxwell R; Reilly, Louise; Eckhardt, Lee L