Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer
HER2-SHCBP1-PLK1轴过度激活促进肿瘤细胞有丝分裂并削弱曲妥珠单抗对胃癌的敏感性
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-021-23053-8
Wengui Shi #, Gengyuan Zhang #, Zhijian Ma #, Lianshun Li #, Miaomiao Liu, Long Qin, Zeyuan Yu, Lei Zhao, Yang Liu, Xue Zhang, Junjie Qin, Huili Ye, Xiangyan Jiang, Huinian Zhou, Hui Sun, Zuoyi Jiao
