NF-κB and AKT signaling prevent DNA damage in transformed pre-B cells by suppressing RAG1/2 expression and activity.
NF-κB 和 AKT 信号通过抑制 RAG1/2 的表达和活性来防止转化前 B 细胞中的 DNA 损伤
期刊:Blood
影响因子:23.1
doi:10.1182/blood-2015-01-621623
Ochodnicka-Mackovicova Katarina, Bahjat Mahnoush, Bloedjes Timon A, Maas Chiel, de Bruin Alexander M, Bende Richard J, van Noesel Carel J M, Guikema Jeroen E J
