Targeting CDK12 disrupts estrogen-receptor chromatin recruitment and ER-MED1 transcription in advanced ER+ breast cancer
靶向 CDK12 会破坏晚期 ER+ 乳腺癌中雌激素受体染色质募集和 ER-MED1 转录
期刊:Jnci-Journal of the National Cancer Institute
影响因子:7.2
doi:10.1093/jnci/djaf295
Ottaviani, Daniela; Ola, Mihaela; Allotta, Alessandra; Maati Chaibi, Yasmine; Hickey, Seán; Jagust, Petra; Cosgrove, Nicola; Cocchiglia, Sinéad; Bane, Fiona; Fallon, Ramón; Daly, Gordon; Hegarty, Aisling; Hudson, Lance; Sheehan, Katherine; Kalsi, Shannon; Shovlin, Stephen; Powell, Aoibhín; Bahl, Ash; Ainscow, Ed; Oesterreich, Steffi; Lee, Adrian V; Couch, Fergus J; Hill, Arnold D K; Varešlija, Damir; Young, Leonie
肿瘤
CDK1
肿瘤免疫
信号转导
MED1
乳腺癌
CDK12
免疫/内分泌
