日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human CAR Tregs Targeting SOD1 and Expressing BDNF Reduce Inflammation and Delay Disease in G93A hSOD1-NSG Mice

靶向SOD1并表达BDNF的人类CAR Tregs可减轻G93A hSOD1-NSG小鼠的炎症并延缓疾病进展

David J Graber ,W James Cook ,Marie-Louise Sentman ,Joana M Murad-Mabaera ,Elijah W Stommel ,Charles L Sentman

Keratinocyte VISTA attenuates UV light-induced skin injury by suppressing cutaneous type I interferon (IFN-I) response

角质形成细胞 VISTA 通过抑制皮肤 I 型干扰素 (IFN-I) 反应来减轻紫外线引起的皮肤损伤。

Peters, Zachary T; Mendyka, Lindsay K; Blake, J'Voughnn; Goswami, Himanshu B; Cortez, Angelique N; Crossland, Grace E; Shan, Sicong; Nowak, Elizabeth C; Mrinal, Sarkar; Johann, E Gudjodsson; Burns, Christopher M; Barton, Dorothea T; Blazar, Bruce R; Curiel, Tyler J; Mabaera, Rodwell; Werth, Victoria P; Kalus, Andrea; Elkon, Keith; Noelle, Randolph J; Skopelja-Gardner, Sladjana

Anti-CD206 CAR T Cell Treatment Restores Fibrosis-Induced Loss of Dermal White Adipose Tissue

抗CD206 CAR T细胞疗法可恢复纤维化引起的真皮白色脂肪组织丢失

Park, Chanhyuk; Mohamed, Asmaa O; Jarnagin, Helen C; Bhandari, Rajan; Gunn, Jason; Murad-Mabaera, Joana; Kosarek, Noelle N; Kolling, Fred W; Wilkins, Owen M; Huang, Yina H; Whitfield, Michael L; Pioli, Patricia A

Human CD4+CD25+ T cells expressing a chimeric antigen receptor against aberrant superoxide dismutase 1 trigger antigen-specific immunomodulation

表达针对异常超氧化物歧化酶 1 的嵌合抗原受体的人类 CD4+CD25+ T 细胞可触发抗原特异性免疫调节

David J Graber,W James Cook,Marie-Louise Sentman,Joana M Murad-Mabaera,Charles L Sentman

Expanding access to early phase trials: the CATCH-UP.2020 experience

扩大早期临床试验的参与机会:CATCH-UP.2020 的经验

Baranda, Joaquina C; Diaz, Francisco J; Rubinstein, Larry; Shields, Anthony F; Dayyani, Farshid; Mehta, Amitkumar; Mehnert, Janice M; Trent, Jonathan; Mabaera, Rodwell; Mooney, Margaret; Moscow, Jeffrey A; Doroshow, James; Waters, Brittany; Ivy, Percy; Gore, Steven D; Thomas, Alexandra

VISTA: A Target to Manage the Innate Cytokine Storm

VISTA:控制先天性细胞因子风暴的靶点

ElTanbouly, Mohamed A; Zhao, Yanding; Schaafsma, Evelien; Burns, Christopher M; Mabaera, Rodwell; Cheng, Chao; Noelle, Randolph J

VISTA Re-programs Macrophage Biology Through the Combined Regulation of Tolerance and Anti-inflammatory Pathways

VISTA 通过耐受性和抗炎途径的联合调节重新编程巨噬细胞生物学

Mohamed A ElTanbouly, Evelien Schaafsma, Nicole C Smits, Parth Shah, Chao Cheng, Christopher Burns, Bruce R Blazar, Randolph J Noelle, Rodwell Mabaera

Hypoxia-Induced VISTA Promotes the Suppressive Function of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

缺氧诱导的 VISTA 促进肿瘤微环境中髓系抑制细胞的抑制功能

Jie Deng, Jiannan Li, Aurelien Sarde, J Louise Lines, Yu-Chi Lee, David C Qian, Dov A Pechenick, Richard Manivanh, Isabelle Le Mercier, Christopher H Lowrey, Frederick S Varn, Chao Cheng, David A Leib, Randolph J Noelle, Rodwell Mabaera

Defining the Signature of VISTA on Myeloid Cell Chemokine Responsiveness

VISTA在髓系细胞趋化因子反应性中的作用机制

Thomas W K Broughton ,Mohamed A ElTanbouly ,Evelien Schaafsma ,Jie Deng ,Aurélien Sarde ,Walburga Croteau ,Jiannan Li ,Elizabeth C Nowak ,Rodwell Mabaera ,Nicole C Smits ,Anna Kuta ,Randolph J Noelle ,J Louise Lines

Metastatic uveal melanoma showing durable response to anti-CTLA-4 and anti-PD-1 combination therapy after experiencing progression on anti-PD-1 therapy alone

转移性葡萄膜黑色素瘤在单独接受抗PD-1治疗后出现疾病进展,但对CTLA-4和PD-1联合治疗表现出持久疗效。

Afzal, Muhammad Zubair; Mabaera, Rodwell; Shirai, Keisuke