日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Comprehensive profiling of chromatin occupancy dynamics through the cell cycle

细胞周期中染色质占据动态的全面分析

Li, Yulong; MacAlpine, David M; Hartemink, Alexander J

Genome-wide nucleosome and transcription factor responses to genetic perturbations reveal chromatin-mediated mechanisms of transcriptional regulation

全基因组核小体和转录因子对遗传扰动的响应揭示了染色质介导的转录调控机制。

Moyung, Kevin; Li, Yulong; MacAlpine, Heather K; Hartemink, Alexander J; MacAlpine, David M

Spt6-Spn1 interaction is required for RNA polymerase II association and precise nucleosome positioning along transcribed genes

Spt6-Spn1相互作用是RNA聚合酶II结合以及核小体沿转录基因精确定位所必需的。

Chen, Boning; Dronamraju, Raghuvar; Smith-Kinnaman, Whitney R; Peck Justice, Sarah A; Hepperla, Austin J; MacAlpine, Heather K; Simon, Jeremy M; Mosley, Amber L; MacAlpine, David M; Strahl, Brian D

Spatiotemporal kinetics of CAF-1-dependent chromatin maturation ensures transcription fidelity during S-phase

CAF-1依赖性染色质成熟的时空动力学确保了S期转录的保真度。

Chen, Boning; MacAlpine, Heather K; Hartemink, Alexander J; MacAlpine, David M

RoboCOP: jointly computing chromatin occupancy profiles for numerous factors from chromatin accessibility data

RoboCOP:利用染色质可及性数据联合计算多种因素的染色质占有率分布图

Mitra, Sneha; Zhong, Jianling; Tran, Trung Q; MacAlpine, David M; Hartemink, Alexander J

Linking the dynamics of chromatin occupancy and transcription with predictive models

将染色质占据和转录的动态变化与预测模型联系起来

Tran, Trung Q; MacAlpine, Heather K; Tripuraneni, Vinay; Mitra, Sneha; MacAlpine, David M; Hartemink, Alexander J

Disruption of origin chromatin structure by helicase activation in the absence of DNA replication

在DNA复制缺失的情况下,解旋酶激活导致起始染色质结构破坏

Rachel A Hoffman ,Heather K MacAlpine ,David M MacAlpine

Capturing the primordial Kras mutation initiating urethane carcinogenesis.

捕获引发氨基甲酸乙酯致癌作用的原始 Kras 突变

Li Siqi, MacAlpine David M, Counter Christopher M

Chromatin conformation and transcriptional activity are permissive regulators of DNA replication initiation in Drosophila

染色质构象和转录活性是果蝇DNA复制起始的允许性调节因子

Armstrong, Robin L; Penke, Taylor J R; Strahl, Brian D; Matera, A Gregory; McKay, Daniel J; MacAlpine, David M; Duronio, Robert J

DNA replication origins-where do we begin?

DNA复制起点——我们从哪里开始?

Prioleau, Marie-Noëlle; MacAlpine, David M