日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Chemogenomic profiling of endogenous PARK2 expression using a genome-edited coincidence reporter

利用基因组编辑的重合报告基因对内源性PARK2表达进行化学基因组学分析

Hasson, Samuel A; Fogel, Adam I; Wang, Chunxin; MacArthur, Ryan; Guha, Rajarshi; Heman-Ackah, Sabrina; Martin, Scott; Youle, Richard J; Inglese, James

Genome editing-enabled HTS assays expand drug target pathways for Charcot-Marie-tooth disease

基因组编辑技术赋能的高通量筛选方法拓展了夏科-马里-图斯病药物靶点通路。

Inglese, James; Dranchak, Patricia; Moran, John J; Jang, Sung-Wook; Srinivasan, Rajini; Santiago, Yolanda; Zhang, Lei; Guha, Rajarshi; Martinez, Natalia; MacArthur, Ryan; Cost, Gregory J; Svaren, John

Titration-based screening for evaluation of natural product extracts: identification of an aspulvinone family of luciferase inhibitors.

基于滴定法的天然产物提取物评价筛选:鉴定出阿斯普维酮类荧光素酶抑制剂

Cruz Patricia G, Auld Douglas S, Schultz Pamela J, Lovell Scott, Battaile Kevin P, MacArthur Ryan, Shen Min, Tamayo-Castillo Giselle, Inglese James, Sherman David H

Comparison of bioluminescent kinase assays using substrate depletion and product formation

比较利用底物消耗和产物生成的生物发光激酶检测方法

Tanega, Cordelle; Shen, Min; Mott, Bryan T; Thomas, Craig J; MacArthur, Ryan; Inglese, James; Auld, Douglas S

Identification of pregnane X receptor ligands using time-resolved fluorescence resonance energy transfer and quantitative high-throughput screening

利用时间分辨荧光共振能量转移和定量高通量筛选技术鉴定孕烷X受体配体

Shukla, Sunita J; Nguyen, Dac-Trung; Macarthur, Ryan; Simeonov, Anton; Frazee, William J; Hallis, Tina M; Marks, Bryan D; Singh, Upinder; Eliason, Hildegard C; Printen, John; Austin, Christopher P; Inglese, James; Auld, Douglas S

A quantitative high-throughput screen for modulators of IL-6 signaling: a model for interrogating biological networks using chemical libraries.

IL-6 信号调节剂的定量高通量筛选:利用化学库研究生物网络的模型

Johnson Ronald L, Huang Ruili, Jadhav Ajit, Southall Noel, Wichterman Jennifer, MacArthur Ryan, Xia Menghang, Bi Kun, Printen John, Austin Christopher P, Inglese James