日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Key transcriptional effectors of the pancreatic acinar phenotype and oncogenic transformation

胰腺腺泡表型和癌变转化的关键转录效应因子

Azevedo-Pouly, Ana; Hale, Michael A; Swift, Galvin H; Hoang, Chinh Q; Deering, Tye G; Xue, Jumin; Wilkie, Thomas M; Murtaugh, L Charles; MacDonald, Raymond J

Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A

PTF1A通过转录维持胰腺腺泡的特性、分化和稳态

Hoang, Chinh Q; Hale, Michael A; Azevedo-Pouly, Ana C; Elsässer, Hans P; Deering, Tye G; Willet, Spencer G; Pan, Fong C; Magnuson, Mark A; Wright, Christopher V E; Swift, Galvin H; MacDonald, Raymond J

MIST1 and PTF1 Collaborate in Feed-Forward Regulatory Loops That Maintain the Pancreatic Acinar Phenotype in Adult Mice.

MIST1 和 PTF1 在前馈调控回路中协同作用,维持成年小鼠的胰腺腺泡表型

Jiang Mei, Azevedo-Pouly Ana C, Deering Tye G, Hoang Chinh Q, DiRenzo Daniel, Hess David A, Konieczny Stephen F, Swift Galvin H, MacDonald Raymond J

The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis

核激素受体家族成员NR5A2在胰腺器官发生过程中控制多能祖细胞的形成和腺泡分化的某些方面。

Hale, Michael A; Swift, Galvin H; Hoang, Chinh Q; Deering, Tye G; Masui, Toshi; Lee, Youn-Kyoung; Xue, Jumin; MacDonald, Raymond J

Dominant and context-specific control of endodermal organ allocation by Ptf1a

Ptf1a 对内胚层器官分配的显性和情境特异性控制

Willet, Spencer G; Hale, Michael A; Grapin-Botton, Anne; Magnuson, Mark A; MacDonald, Raymond J; Wright, Christopher V E

Program specificity for Ptf1a in pancreas versus neural tube development correlates with distinct collaborating cofactors and chromatin accessibility

Ptf1a在胰腺发育和神经管发育中的程序特异性与不同的协同辅助因子和染色质可及性相关。

Meredith, David M; Borromeo, Mark D; Deering, Tye G; Casey, Bradford H; Savage, Trisha K; Mayer, Paul R; Hoang, Chinh; Tung, Kuang-Chi; Kumar, Manonmani; Shen, Chengcheng; Swift, Galvin H; Macdonald, Raymond J; Johnson, Jane E

Notch-mediated patterning and cell fate allocation of pancreatic progenitor cells

Notch介导的胰腺祖细胞模式形成和细胞命运分配

Afelik, Solomon; Qu, Xiaoling; Hasrouni, Edy; Bukys, Michael A; Deering, Tye; Nieuwoudt, Stephan; Rogers, William; Macdonald, Raymond J; Jensen, Jan

Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism

Ptf1a介导的Dll1调控揭示了侧向抑制机制之外的另一种机制。

Ahnfelt-Rønne, Jonas; Jørgensen, Mette C; Klinck, Rasmus; Jensen, Jan N; Füchtbauer, Ernst-Martin; Deering, Tye; MacDonald, Raymond J; Wright, Chris V E; Madsen, Ole D; Serup, Palle

Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells

PTF1复合物中Rbpj被Rbpjl取代,控制着胰腺腺泡细胞的最终成熟。

Masui, Toshihiko; Swift, Galvin H; Deering, Tye; Shen, Chengcheng; Coats, Ward S; Long, Qiaoming; Elsässer, Hans-Peter; Magnuson, Mark A; MacDonald, Raymond J

Conditional control of the differentiation competence of pancreatic endocrine and ductal cells by Fgf10

Fgf10对胰腺内分泌细胞和导管细胞分化能力的条件性调控

Kobberup, Sune; Schmerr, Martin; Dang, My-Linh; Nyeng, Pia; Jensen, Jan N; MacDonald, Raymond J; Jensen, Jan