日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Galectin-1 Induces the Production of Immune-Suppressive Cytokines in Human and Mouse T Cells.

半乳糖凝集素-1诱导人和小鼠T细胞产生免疫抑制细胞因子

Herman Kimberly D, Holyer Ian, Humphries Duncan C, Adamska Anna, Roper James A, Peterson Kristoffer, Zetterberg Fredrik R, Pedersen Anders, MacKinnon Alison C, Slack Robert J

An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE)

吸入型半乳糖凝集素-3抑制剂治疗COVID-19肺炎:一项Ib/IIa期随机对照临床试验(DEFINE)

Gaughan, Erin E; Quinn, Tom M; Mills, Andrew; Bruce, Annya M; Antonelli, Jean; MacKinnon, Alison C; Aslanis, Vassilios; Li, Feng; O'Connor, Richard; Boz, Cecilia; Mills, Ross; Emanuel, Philip; Burgess, Matthew; Rinaldi, Giulia; Valanciute, Asta; Mills, Bethany; Scholefield, Emma; Hardisty, Gareth; Findlay, Emily Gwyer; Parker, Richard A; Norrie, John; Dear, James W; Akram, Ahsan R; Koch, Oliver; Templeton, Kate; Dockrell, David H; Walsh, Timothy S; Partridge, Stephen; Humphries, Duncan; Wang-Jairaj, Jie; Slack, Robert J; Schambye, Hans; Phung, De; Gravelle, Lise; Lindmark, Bertil; Shankar-Hari, Manu; Hirani, Nikhil; Sethi, Tariq; Dhaliwal, Kevin

Safety and pharmacokinetics of GB1211, an oral galectin-3 inhibitor: a single- and multiple-dose first-in-human study in healthy participants

GB1211(一种口服半乳糖凝集素-3抑制剂)的安全性和药代动力学:一项在健康受试者中进行的单剂量和多剂量首次人体研究

Aslanis, Vassilios; Slack, Robert J; MacKinnon, Alison C; McClinton, Catherine; Tantawi, Susan; Gravelle, Lise; Nilsson, Ulf J; Leffler, Hakon; Brooks, Ashley; Khindri, Sanjeev K; Marshall, Richard P; Pedersen, Anders; Schambye, Hans; Zetterberg, Fredrik

Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis.

吸入TD139对特发性肺纤维化患者进行半乳糖凝集素-3靶向抑制

Hirani Nikhil, MacKinnon Alison C, Nicol Lisa, Ford Paul, Schambye Hans, Pedersen Anders, Nilsson Ulf J, Leffler Hakon, Sethi Tariq, Tantawi Susan, Gravelle Lise, Slack Robert J, Mills Ross, Karmakar Utsa, Humphries Duncan, Zetterberg Fredrik, Keeling Lucy, Paul Lyn, Molyneaux Philip L, Li Feng, Funston Wendy, Forrest Ian A, Simpson A John, Gibbons Michael A, Maher Toby M

Phenotypic and functional characterization of macrophages with therapeutic potential generated from human cirrhotic monocytes in a cohort study

在一项队列研究中,对由人肝硬化单核细胞生成的具有治疗潜力的巨噬细胞进行表型和功能表征

Moore, Joanna K; Mackinnon, Alison C; Wojtacha, Dvina; Pope, Caroline; Fraser, Alasdair R; Burgoyne, Paul; Bailey, Laura; Pass, Chloe; Atkinson, Anne; Mcgowan, Neil W A; Manson, Lynn; Turner, Mark L; Campbell, John D M; Forbes, Stuart J

Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis

半乳糖凝集素-3的表达和分泌将巨噬细胞与肾纤维化的促进联系起来

Henderson, Neil C; Mackinnon, Alison C; Farnworth, Sarah L; Kipari, Tiina; Haslett, Christopher; Iredale, John P; Liu, Fu-Tong; Hughes, Jeremy; Sethi, Tariq

Galectin-3 reduces the severity of pneumococcal pneumonia by augmenting neutrophil function

半乳糖凝集素-3通过增强中性粒细胞功能来减轻肺炎球菌性肺炎的严重程度。

Farnworth, Sarah L; Henderson, Neil C; Mackinnon, Alison C; Atkinson, Kirsten M; Wilkinson, Tom; Dhaliwal, Kevin; Hayashi, Katsutoshi; Simpson, A John; Rossi, Adriano G; Haslett, Christopher; Sethi, Tariq

Cross-linking CD98 promotes integrin-like signaling and anchorage-independent growth

CD98交联促进整合素样信号传导和非锚定依赖性生长

Rintoul, Robert C; Buttery, Robert C; Mackinnon, Alison C; Wong, Weng Sie; Mosher, Deane; Haslett, Christopher; Sethi, Tariq