日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Beyond Histology: A Unified Transcriptomic Atlas Defines Lung Cancer Biologic States and Subtypes

超越组织学:统一转录组图谱定义肺癌生物学状态和亚型

Arora, Sonali; Suresh, Laavan; Thirimanne, H Nayanga; Glatzer, Gregory; Jensen, Matt; Fatherree, Jackson P; Konnick, Eric Q; Levine, Kevin M; Brooks, Angela N; Hougton, A McGarry; Pritchard, Colin C; MacPherson, David; Berger, Alice H; Holland, Eric C

Deep learning-based non-invasive profiling of tumor transcriptomes from cell-free DNA for precision oncology.

基于深度学习的无细胞DNA肿瘤转录组非侵入性分析,用于精准肿瘤学。

Patton Robert D, Netzley Alexander, Persse Thomas W, Nair Akira, Galipeau Patricia C, Coleman Ilsa M, Itagi Pushpa, Chandra Pooja, Adil Mohamed, Vashisth Manasvita, Sayar Erolcan, Hiatt Joseph B, Dumpit Ruth, Kollath Lori, Demirci Ridvan Arda, Ghodsi Alireza, Lam Hung-Ming, Morrissey Colm, Iravani Amir, Chen Delphine L, Hsieh Andrew C, MacPherson David, Haffner Michael C, Nelson Peter S, Ha Gavin

The Lung Cancer Autochthonous Model Gene Expression Database Enables Cross-Study Comparisons of the Transcriptomic Landscapes Across Mouse Models

肺癌自体模型基因表达数据库能够对不同小鼠模型的转录组图谱进行跨研究比较

Cai, Ling; Wu, Fangjiang; Zhou, Qinbo; Gao, Ying; Yao, Bo; DeBerardinis, Ralph J; Acquaah-Mensah, George K; Aidinis, Vassilis; Beane, Jennifer E; Biswal, Shyam; Chen, Ting; Concepcion-Crisol, Carla P; Grüner, Barbara M; Jia, Deshui; Jones, Robert A; Kurie, Jonathan M; Lee, Min Gyu; Lindahl, Per; Lissanu, Yonathan; Lorz, Corina; MacPherson, David; Martinelli, Rosanna; Mazur, Pawel K; Mazzilli, Sarah A; Mii, Shinji; Moll, Herwig P; Moorehead, Roger A; Morrisey, Edward E; Ng, Sheng Rong; Oser, Matthew G; Pandiri, Arun R; Powell, Charles A; Ramadori, Giorgio; Santos, Mirentxu; Snyder, Eric L; Sotillo, Rocio; Su, Kang-Yi; Taki, Tetsuro; Taparra, Kekoa; Tran, Phuoc T; Xia, Yifeng; van Veen, J Edward; Winslow, Monte M; Xiao, Guanghua; Rudin, Charles M; Oliver, Trudy G; Xie, Yang; Minna, John D

MAX inactivation deregulates the MYC network and induces neuroendocrine neoplasia in multiple tissues.

MAX失活会扰乱MYC网络,并在多种组织中诱发神经内分泌肿瘤

Freie Brian, Ibrahim Ali H, Carroll Patrick A, Bronson Roderick T, Augert Arnaud, MacPherson David, Eisenman Robert N

In vivo functional screens reveal KEAP1 loss as a driver of chemoresistance in small cell lung cancer.

体内功能筛选揭示 KEAP1 缺失是小细胞肺癌化疗耐药性的驱动因素

Brumage Lauren, Best Scott, Hippe Daniel S, Grunblatt Eli, Chanana Pritha, Wu Feinan, Lee Myung Chang, Ying Zhe, Ibrahim Ali, Chung Jae Heun, Vigil Anna, Fatherree Jackson, Beronja Slobodan, Paddison Patrick, Sullivan Lucas, Nabet Barzin, MacPherson David

Genetically-engineered mouse models of small cell lung cancer: the next generation

小细胞肺癌的基因工程小鼠模型:下一代

Oser, Matthew G; MacPherson, David; Oliver, Trudy G; Sage, Julien; Park, Kwon-Sik

New Approaches to SCLC Therapy: From the Laboratory to the Clinic

小细胞肺癌治疗的新方法:从实验室到临床

Poirier, John T; George, Julie; Owonikoko, Taofeek K; Berns, Anton; Brambilla, Elisabeth; Byers, Lauren A; Carbone, David; Chen, Huanhuan J; Christensen, Camilla L; Dive, Caroline; Farago, Anna F; Govindan, Ramaswamy; Hann, Christine; Hellmann, Matthew D; Horn, Leora; Johnson, Jane E; Ju, Young S; Kang, Sumin; Krasnow, Mark; Lee, James; Lee, Se-Hoon; Lehman, Jonathan; Lok, Benjamin; Lovly, Christine; MacPherson, David; McFadden, David; Minna, John; Oser, Matthew; Park, Keunchil; Park, Kwon-Sik; Pommier, Yves; Quaranta, Vito; Ready, Neal; Sage, Julien; Scagliotti, Giorgio; Sos, Martin L; Sutherland, Kate D; Travis, William D; Vakoc, Christopher R; Wait, Sarah J; Wistuba, Ignacio; Wong, Kwok Kin; Zhang, Hua; Daigneault, Jillian; Wiens, Jacinta; Rudin, Charles M; Oliver, Trudy G

Discovery of Vixotrigine: A Novel Use-Dependent Sodium Channel Blocker for the Treatment of Trigeminal Neuralgia

发现Vixotrigine:一种用于治疗三叉神经痛的新型用药依赖性钠通道阻滞剂

Witty, David R; Alvaro, Giuseppe; Derjean, Dominique; Giblin, Gerard M P; Gunn, Kevin; Large, Charles; Macpherson, David T; Morisset, Valerie; Owen, Davina; Palmer, Joanne; Rugiero, Francois; Tate, Simon; Hinckley, Christopher A; Naik, Himanshu

Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data

小细胞肺癌的分子亚型:人和小鼠模型数据的综合分析

Rudin, Charles M; Poirier, John T; Byers, Lauren Averett; Dive, Caroline; Dowlati, Afshin; George, Julie; Heymach, John V; Johnson, Jane E; Lehman, Jonathan M; MacPherson, David; Massion, Pierre P; Minna, John D; Oliver, Trudy G; Quaranta, Vito; Sage, Julien; Thomas, Roman K; Vakoc, Christopher R; Gazdar, Adi F

Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance)

小细胞肺癌表现出组蛋白甲基转移酶 KMT2D/MLL2 的频繁失活突变:CALGB 151111(联盟)

Augert, Arnaud; Zhang, Qing; Bates, Breanna; Cui, Min; Wang, Xiaofei; Wildey, Gary; Dowlati, Afshin; MacPherson, David