NOTCH1 S2513 is critical for the regulation of NICD levels impacting the segmentation clock in hiPSC-derived PSM cells and somitoids.
NOTCH1 S2513 对 hiPSC 衍生的 PSM 细胞和体节中的 NICD 水平的调节至关重要,从而影响节段时钟
期刊:Genes & Development
影响因子:7.7
doi:10.1101/gad.352909.125
Meijer Hedda A, Hetherington Adam, Johnson Sara J, Gallagher Rosie L, Hussein Izzah N, Weng Yuqi, Rae Jess M, Noordzij Tomas E J C, Kalamara Margarita, Macartney Thomas J, Davidson Lindsay, Martin David M A, Gierlinski Marek, Davies Paul, Sonnen Katharina F, Murray Philip J, Dale J Kim