日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss

M1毒蕈碱受体变构调节剂可减缓朊病毒引起的神经退行性变并恢复记忆丧失

Bradley, Sophie J; Bourgognon, Julie-Myrtille; Sanger, Helen E; Verity, Nicholas; Mogg, Adrian J; White, David J; Butcher, Adrian J; Moreno, Julie A; Molloy, Colin; Macedo-Hatch, Timothy; Edwards, Jennifer M; Wess, Jurgen; Pawlak, Robert; Read, David J; Sexton, Patrick M; Broad, Lisa M; Steinert, Joern R; Mallucci, Giovanna R; Christopoulos, Arthur; Felder, Christian C; Tobin, Andrew B

Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction

绘制生理性G蛋白偶联受体信号通路图谱揭示了受体磷酸化在气道收缩中的作用

Bradley, Sophie J; Wiegman, Coen H; Iglesias, Max Maza; Kong, Kok Choi; Butcher, Adrian J; Plouffe, Bianca; Goupil, Eugénie; Bourgognon, Julie-Myrtille; Macedo-Hatch, Timothy; LeGouill, Christian; Russell, Kirsty; Laporte, Stéphane A; König, Gabriele M; Kostenis, Evi; Bouvier, Michel; Chung, Kian Fan; Amrani, Yassine; Tobin, Andrew B

An Antibody Biosensor Establishes the Activation of the M1 Muscarinic Acetylcholine Receptor during Learning and Memory

抗体生物传感器可确定学习和记忆过程中M1毒蕈碱乙酰胆碱受体的激活情况

Butcher, Adrian J; Bradley, Sophie J; Prihandoko, Rudi; Brooke, Simon M; Mogg, Adrian; Bourgognon, Julie-Myrtille; Macedo-Hatch, Timothy; Edwards, Jennifer M; Bottrill, Andrew R; Challiss, R A John; Broad, Lisa M; Felder, Christian C; Tobin, Andrew B