日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Molecular and Antiangiogenic Effects of Paclitaxel-Loaded Nanoparticles: Influence of the Nanocarrier Type

紫杉醇纳米粒子的分子和抗血管生成效应：纳米载体类型的影响

期刊:Molecular Pharmaceutics
影响因子:4.5
doi:10.1021/acs.molpharmaceut.5c01740
Passos, Julia Sapienza; de Melo, Giovanna B; Salata, Giovanna C; Machado-Neto, João Agostinho; Panitch, Alyssa; Lopes, Luciana B
血管生成
发表日期：2026
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Dona Flor and her two husbands: Discovery of novel HDAC6/AKT2 inhibitors for myeloid cancer treatment

唐娜·弗洛尔和她的两位丈夫：发现用于治疗髓系癌症的新型HDAC6/AKT2抑制剂

期刊:Computers in Biology and Medicine
影响因子:6.3
doi:10.1016/j.compbiomed.2025.110990
Waitman, Karoline B; Martin, Holli-Joi; Carlos, Jorge A E G; Braga, Rodolpho C; Souza, Vinícius A M; Melo-Filho, Cleber C; Hilscher, Sebastian; Toledo, Mônica F Z J; Tavares, Maurício T; Costa-Lotufo, Letícia V; Machado-Neto, João A; Schutkowski, Mike; Sippl, Wolfgang; Kronenberger, Thales; Alves, Vinicius M; Parise-Filho, Roberto; Muratov, Eugene N
肿瘤
肿瘤免疫
AKT2
HDAC6
AKT
发表日期：2025
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Synthesis and Evaluation of 2‑Substituted Quinazolin-4(3H)‑ones as Potential Antileukemic Agents.

2'取代喹唑啉-4(3H)'酮的合成与评价及其作为潜在抗白血病药物的潜力

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.5c04106
Antoniolli Giorgio, Lima Keli, Franchi Gilberto Carlos, Lima Carmen Silvia Passos, Machado-Neto João Agostinho, Coelho Fernando
其它
药物研究
发表日期：2025
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Cephalochromin Effects in Triple-Negative Breast Cancer Cells: Apoptosis Induction and Modulation of Survival Pathways

头孢色胺对三阴性乳腺癌细胞的影响：诱导细胞凋亡和调节生存通路

期刊:Journal of Natural Products
影响因子:3.6
doi:10.1021/acs.jnatprod.5c01020
Diccini, Isabelle; Parducci, Natália Sudan; de Almeida, Bruna Oliveira; Farinella, Victor; Dos Santos, Patrick Castilho; de Miranda, Livia Bassani Lins; Botelho, Sabrina Mendes; Lima, Keli; Carlos, Jorge Antonio Elias Godoy; Garnique, Anali Del Milagro Bernabe; Pena Ferreira, Marcelo José; Costa-Lotufo, Leticia Veras; Machado-Neto, João Agostinho
肿瘤
凋亡
表观遗传
肿瘤免疫
Apoptosis
信号转导
乳腺癌
细胞生物学
发表日期：2025
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A decision support system to recommend appropriate therapy protocol for AML patients

为急性髓系白血病患者推荐合适治疗方案的决策支持系统

期刊:Frontiers in Artificial Intelligence
影响因子:4.7
doi:10.3389/frai.2024.1343447
Castro, Giovanna A; Almeida, Jade M; Machado-Neto, João A; Almeida, Tiago A
白血病
发表日期：2024
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Autophagy and inflammasome activation are associated with poor response to FLT3 inhibitors in patients with FLT3-ITD acute myeloid leukemia

自噬和炎症小体激活与 FLT3-ITD 急性髓系白血病患者对 FLT3 抑制剂反应不佳有关

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-024-74168-z
Brunno Gilberto Santos de Macedo, Manuela Albuquerque de Melo, Diego Antonio Pereira-Martins, João Agostinho Machado-Neto, Fabíola Traina
免疫
白血病
Autophagy
发表日期：2024
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Comprehensive analysis of the HCK gene in myeloid neoplasms: Insights into biological functions, prognosis, and response to antineoplastic agents

髓系肿瘤中 HCK 基因的综合分析：深入了解其生物学功能、预后和对抗肿瘤药物的反应

期刊:Hematology Transfusion and Cell Therapy
影响因子:1.8
doi:10.1016/j.htct.2023.11.007
Maria Fernanda Lopes Carvalho, Bruna Oliveira de Almeida, Maura Lima Pereira Bueno, Hugo Passos Vicari, Keli Lima, Eduardo Magalhães Rego, Fernanda Marconi Roversi, João Agostinho Machado-Neto
肿瘤
发表日期：2024
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Clinical significance of Philadelphia-like-related genes in a resource-constrained setting of adult B-acute lymphoblastic leukemia patients

在资源匮乏的成人B细胞急性淋巴细胞白血病患者中，费城染色体样相关基因的临床意义

期刊:eJHaem
影响因子:1.2
doi:10.1002/jha2.1030
Lima, Keli; Rojas, César Alexander Ortiz; Nogueira, Frederico Lisboa; da Silva, Wellington Fernandes; Cavaglieri, Rita de Cássia; Nardinelli, Luciana; Leal, Aline de Medeiros; Velloso, Elvira Deolinda Rodrigues Pereira; Bendit, Israel; Alencar, Alvaro; Mullighan, Charles G; Machado-Neto, João Agostinho; Rego, Eduardo Magalhães
白血病
细胞生物学
B细胞
免疫/内分泌
发表日期：2024
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Transcriptomics analysis identified ezrin as a potential druggable target in cervical and gastric cancer cells

转录组学分析确定埃兹林是宫颈癌和胃癌细胞中潜在的可用药靶点

期刊:Clinics (Sao Paulo)
影响因子:
doi:10.1016/j.clinsp.2024.100422
Maria Fernanda Lopes Carvalho, Carolina Santana Calicchio, Bruna Oliveira de Almeida, Livia Bassani Lins de Miranda, Jean Carlos Lipreri da Silva, Keli Lima, João Agostinho Machado-Neto
免疫
细胞生物学
宫颈癌
胃癌
肿瘤细胞
发表日期：2024
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1,3-Diphenylureido hydroxamate as a promising scaffold for generation of potent antimalarial histone deacetylase inhibitors

1,3-二苯脲基异羟肟酸酯是一种有前途的支架，可用于生成有效的抗疟组蛋白去乙酰化酶抑制剂

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-023-47959-z
Maurício T Tavares #, Arne Krüger #, Sun L Rei Yan, Karoline B Waitman, Vinícius M Gomes, Daffiny Sumam de Oliveira, Franciarli Paz, Sebastian Hilscher, Mike Schutkowski, Wolfgang Sippl, Claudia Ruiz, Mônica F Z J Toledo, Neuza M A Hassimotto, João A Machado-Neto, Antti Poso, Michael D Cameron, Thom
表观遗传
发表日期：2023
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