日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Phosphorylation of Runx protein controls helper CD4(+) T cell versus cytotoxic CD8(+) T cell lineage choice

Runx蛋白的磷酸化控制辅助性CD4(+) T细胞与细胞毒性CD8(+) T细胞的谱系选择

期刊:Nature Immunology
影响因子:27.6
doi:10.1038/s41590-026-02441-6
Ogawa, Chihiro; Okuyama, Kazuki; Kojo, Satoshi; Nishino, Kohei; Machiyama, Hiroaki; Padhi, Aditya K; Takahashi, Hirotaka; Ebihara, Takashi; Tenno, Mari; Zhizhen, Qin; Muroi, Sawako; Ito, Kosei; Sawasaki, Tatsuya; Zhang, Kam Y J; Xue, Hai-Hui; Yokosuka, Tadashi; Kosako, Hidetaka; Taniuchi, Ichiro
T细胞
信号转导
CD8
T细胞
磷酸化
细胞生物学
毒理研究
CD4
免疫/内分泌
发表日期：2026
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Dynamic Remodeling of Mechano-Sensing Complexes in Suspended Fibroblast Cell-Sheets Under External Mechanical Stimulus.

悬浮成纤维细胞片层在外部机械刺激下的机械感受复合物的动态重塑

期刊:Biotechnology and Bioengineering
影响因子:3.6
doi:10.1002/bit.28996
Suzuki Madoka, Kawauchi Keiko, Machiyama Hiroaki, Hirata Hiroaki, Ishiwata Shin'ichi, Fujita Hideaki
细胞生物学
发表日期：2025
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A Multicenter, Retrospective, Real-World Study of Atezolizumab Plus Chemotherapy and Pembrolizumab Plus Chemotherapy for Older Patients With NSCLC

一项多中心、回顾性、真实世界研究，比较阿特珠单抗联合化疗和帕博利珠单抗联合化疗治疗老年非小细胞肺癌患者的疗效。

期刊:JTO Clinical and Research Reports
影响因子:3.5
doi:10.1016/j.jtocrr.2025.100891
Kanaoka, Kensuke; Matsumoto, Kinnosuke; Shiroyama, Takayuki; Tsukaguchi, Akihiro; Shoshihara, Nao; Moritomo, Koki; Kinehara, Yuhei; Mihashi, Yasuhiro; Kuge, Tomoki; Yoneda, Midori; Kato, Soichiro; Yamauchi, Keijiro; Machiyama, Hirotomo; Nishikawa, Yuki; Morimura, Osamu; Miyazaki, Akito; Komuta, Kiyohide; Azuma, Kouji; Tanaka, Satoshi; Niki, Toshie; Osa, Akio; Tamiya, Akihiro; Tamiya, Motohiro; Suzuki, Hidekazu; Mori, Masahide; Takeda, Yoshito; Kumanogoh, Atsushi
肺癌
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
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Imaging of biphasic signalosomes constructed by checkpoint receptor 2B4 in conventional and chimeric antigen receptor-T cells

对常规和嵌合抗原受体T细胞中由检查点受体2B4构建的双相信号体进行成像

期刊:iScience
影响因子:4.6
doi:10.1016/j.isci.2024.111669
Ryohei Matsushima ，Ei Wakamatsu ，Hiroaki Machiyama ，Wataru Nishi ，Yosuke Yoshida ，Tetsushi Nishikawa ，Hiroko Toyota ，Masae Furuhata ，Hitoshi Nishijima ，Arata Takeuchi ，Makoto Suzuki ，Tadashi Yokosuka
细胞生物学
免疫/内分泌
T细胞
T细胞
信号转导
发表日期：2024
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Imaging of biphasic signalosomes constructed by checkpoint receptor 2B4 in conventional and chimeric antigen receptor-T cells

对常规和嵌合抗原受体T细胞中由检查点受体2B4构建的双相信号体进行成像

期刊:
影响因子:4.6
doi:PMC11780131
Ryohei Matsushima，Ei Wakamatsu，Hiroaki Machiyama，Wataru Nishi，Yosuke Yoshida，Tetsushi Nishikawa，Hiroko Toyota，Masae Furuhata，Hitoshi Nishijima，Arata Takeuchi，Makoto Suzuki，Tadashi Yokosuka
信号转导
细胞生物学
T细胞
Checkpoint
T细胞
发表日期：2024
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Electrical resistivity tomography combined with seismic data estimates heterogeneous distribution of near-seafloor concentrated gas hydrates within gas chimneys

电阻率层析成像结合地震数据估算出海底附近高浓度天然气水合物在气烟囱内的分布不均匀

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-024-65817-4
Ishizu, Keiichi; Oda, Ayako; Goto, Tada-Nori; Kasaya, Takafumi; Watanabe, Toshiki; Machiyama, Hideaki
发表日期：2024
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Evaluation of therapeutic PD-1 antibodies by an advanced single-molecule imaging system detecting human PD-1 microclusters

利用先进的单分子成像系统检测人PD-1微簇，评估治疗性PD-1抗体

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-023-38512-7
Wataru Nishi ，Ei Wakamatsu ，Hiroaki Machiyama ，Ryohei Matsushima ，Kensho Saito ，Yosuke Yoshida ，Tetsushi Nishikawa ，Tomohiro Takehara ，Hiroko Toyota ，Masae Furuhata ，Hitoshi Nishijima ，Arata Takeuchi ，Miyuki Azuma ，Makoto Suzuki ，Tadashi Yokosuka
PD-1
发表日期：2023
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Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8+ T cell cytotoxicity and proliferation

肿瘤衍生的信号蛋白 4A 通过增强 CD8+ T 细胞的细胞毒性和增殖来提高 PD-1 阻断抗体的疗效

期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.ade0718
Yujiro Naito, Shohei Koyama, Kentaro Masuhiro, Takashi Hirai, Takeshi Uenami, Takako Inoue, Akio Osa, Hirotomo Machiyama, Go Watanabe, Nicolas Sax, Jordan Villa, Yumi Kinugasa-Katayama, Satoshi Nojima, Moto Yaga, Yuki Hosono, Daisuke Okuzaki, Shingo Satoh, Takeshi Tsuda, Yoshimitsu Nakanishi, Yasuhi
信号转导
肿瘤
T细胞
T Cell Receptor
发表日期：2023
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Actin crosslinking by α-actinin averts viscous dissipation of myosin force transmission in stress fibers

肌动蛋白通过α-肌动蛋白交联可避免肌球蛋白力在应力纤维中传递的粘性耗散

期刊:iScience
影响因子:4.6
doi:10.1016/j.isci.2023.106090
Hiroki Katsuta, Satoru Okuda, Kazuaki Nagayama, Hiroaki Machiyama, Satoru Kidoaki, Masashi Kato, Masahiro Sokabe, Takaki Miyata, Hiroaki Hirata
信号转导
发表日期：2023
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Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2

NSD2 调控核小体组蛋白 H3 Lys36 正常及致癌甲基化的结构基础

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-021-26913-5
Ko Sato #, Amarjeet Kumar, Keisuke Hamada, Chikako Okada, Asako Oguni, Ayumi Machiyama, Shun Sakuraba, Tomohiro Nishizawa, Osamu Nureki, Hidetoshi Kono, Kazuhiro Ogata, Toru Sengoku #
肿瘤
发表日期：2021
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