日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ex Vivo Drug Sensitivity Correlates with Clinical Response and Supports Personalized Therapy in Pediatric AML

体外药物敏感性与临床反应相关,支持儿童 AML 的个性化治疗

Debbie C Strachan, Christine J Gu, Ryosuke Kita, Erica K Anderson, Michelle A Richardson, George Yam, Graham Pimm, Jordan Roselli, Alyssa Schweickert, Maci Terrell, Raushan Rashid, Alan K Gonzalez, Hailey H Oviedo, Michelle C Alozie, Tamilini Ilangovan, Andrea N Marcogliese, Hiroomi Tada, Marianne T

Defining the transcriptional control of pediatric AML highlights RARA as a superenhancer-regulated druggable dependency

定义儿童 AML 的转录控制突出了 RARA 是一种超增强子调节的可用药依赖性

Monika W Perez, Oscar Sias-Garcia, Alfred Daramola, Helen Wei, Maci Terrell, Raushan Rashid, Woojun D Park, Kevin Duong, Terzah M Horton, Feng Li, Nikitha Cherayil, Jost Vrabic Koren, Vincent U Gant, Jacob J Junco, Choladda V Curry, Alexandra M Stevens, Charles Y Lin, Joanna S Yi

Enhancer polymorphisms at the IKZF1 susceptibility locus for acute lymphoblastic leukemia impact B-cell proliferation and differentiation in both Down syndrome and non-Down syndrome genetic backgrounds

急性淋巴细胞白血病 IKZF1 易感基因座的增强子多态性影响唐氏综合征和非唐氏综合征遗传背景下的 B 细胞增殖和分化

Vincent U Gant, Jacob J Junco, Maci Terrell, Raushan Rashid, Karen R Rabin