Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine.
通过对 CaaX 盒半胱氨酸进行直接共价攻击,阻断 KRAS4b 的 C 端加工
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2410766122
Maciag Anna E, Yang Yue, Sharma Alok K, Turner David M, DeHart Caroline J, Abdelkarim Hazem, Fan Lixin, Smith Brian P, Kumari Vandana, Dyba Marcin, Rigby Megan, Castillo Badillo Jean A, Adams Lauren, Fornelli Luca, Fox Stephen, Brafman Alla, Turbyville Thomas, Gillette William, Messing Simon, Agamasu Constance, Wolfe Andrew L, Gysin Stephan, Chan Albert H, Simanshu Dhirendra K, Esposito Dominic, Chertov Oleg, Stephen Andrew G, Arkin Michelle, Renslo Adam, Kelleher Neil L, Gaponenko Vadim, Lightstone Felice C, Nissley Dwight V, McCormick Frank