日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ω-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase

Ω环突变通过调节PDC-3 β-内酰胺酶中的氢键网络来控制活性位点的动力学。

Chen, Shuang; Mack, Andrew R; Hujer, Andrea M; Bethel, Christopher R; Bonomo, Robert A; Haider, Shozeb

Direct Binding of Lyn to GPIbβ Transmits 2-Way GPIb-IX Signaling to Stimulate Platelet Activation and VWF Binding

Lyn 与 GPIbβ 的直接结合传递双向 GPIb-IX 信号,从而刺激血小板活化和 VWF 结合。

Zhang, Yaping; Liang, Ying; Kazemipour Ashkezari, Amir Hossein; Wang, Can; Chang, Claire W; Bai, Yanyan; Huang, Xin; Mack, Andrew; Yang, Haotian; Cong, Peiwen; Cheng, Ni; Zhu, Cheng; Du, Xiaoping

β-Lactamase diversity in Pseudomonas aeruginosa

铜绿假单胞菌中β-内酰胺酶的多样性

Mack, Andrew R; Hujer, Andrea M; Mojica, Maria F; Taracila, Magdalena A; Feldgarden, Michael; Haft, Daniel H; Klimke, William; Prasad, Arjun B; Bonomo, Robert A

β-Lactamase diversity in Acinetobacter baumannii

鲍曼不动杆菌中β-内酰胺酶的多样性

Mack, Andrew R; Hujer, Andrea M; Mojica, Maria F; Taracila, Magdalena A; Feldgarden, Michael; Haft, Daniel H; Klimke, William; Prasad, Arjun B; Bonomo, Robert A

Structure and mechanism of taniborbactam inhibition of the cefepime-hydrolyzing, partial R2-loop deletion Pseudomonas-derived cephalosporinase variant PDC-88

坦尼博巴坦抑制头孢吡肟水解酶、部分R2环缺失的假单胞菌来源头孢菌素酶变体PDC-88的结构和机制

Mack, Andrew R; Kumar, Vijay; Bethel, Christopher R; Taracila, Magdalena A; Miller, Brittany A; Uehara, Tsuyoshi; Six, David A; Papp-Wallace, Krisztina M; van den Akker, Focco; Bonomo, Robert A

Ω-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase

Ω环突变通过调节PDC-3 β-内酰胺酶中的氢键网络来控制活性位点的动力学。

Chen, Shuang; Mack, Andrew R; Hujer, Andrea M; Bethel, Christopher R; Bonomo, Robert A; Haider, Shozeb

Thromboinflammation and the Role of Platelets

血栓炎症及血小板的作用

Mack, Andrew; Vanden Hoek, Terry; Du, Xiaoping

ARGONAUT-III and -V: susceptibility of carbapenem-resistant Klebsiella pneumoniae and multidrug-resistant Pseudomonas aeruginosa to the bicyclic boronate β-lactamase inhibitor taniborbactam combined with cefepime

ARGONAUT-III 和 -V:碳青霉烯类耐药肺炎克雷伯菌和多重耐药铜绿假单胞菌对双环硼酸β-内酰胺酶抑制剂他尼博巴坦联合头孢吡肟的敏感性

Jacobs, Michael R; Abdelhamed, Ayman M; Good, Caryn E; Mack, Andrew R; Bethel, Christopher R; Marshall, Steven; Hujer, Andrea M; Hujer, Kristine M; Patel, Robin; van Duin, David; Fowler, Vance G; Rhoads, Daniel D; Six, David A; Moeck, Greg; Uehara, Tsuyoshi; Papp-Wallace, Krisztina M; Bonomo, Robert A

ARGONAUT-IV: susceptibility of carbapenemase-producing Klebsiella pneumoniae to the oral bicyclic boronate β-lactamase inhibitor ledaborbactam combined with ceftibuten

ARGONAUT-IV:产碳青霉烯酶肺炎克雷伯菌对口服双环硼酸β-内酰胺酶抑制剂ledaborbactam联合头孢布烯的敏感性

Jacobs, Michael R; Good, Caryn E; Abdelhamed, Ayman M; Mack, Andrew R; Bethel, Christopher R; Marshall, Steven H; Hujer, Andrea M; Hujer, Kristine M; Patel, Robin; van Duin, David; Fowler, Vance G; Rhoads, Daniel D; Six, David A; Moeck, Greg; Uehara, Tsuyoshi; Papp-Wallace, Krisztina M; Bonomo, Robert A

A Proofreading Mutation with an Allosteric Effect Allows a Cluster of SARS-CoV-2 Viruses to Rapidly Evolve

一种具有变构效应的校对突变使得一群SARS-CoV-2病毒能够快速进化

Mack, Andrew H; Menzies, Georgina; Southgate, Alex; Jones, D Dafydd; Connor, Thomas R