Mackenzie Amanda E相关文献与解析，生知库

Marti-Solano Maria, Crilly Stephanie E, Malinverni Duccio, Munk Christian, Harris Matthew, Pearce Abigail, Quon Tezz, Mackenzie Amanda E, Wang Xusheng, Peng Junmin, Tobin Andrew B, Ladds Graham, Milligan Graeme, Gloriam David E, Puthenveedu Manojkumar A, Babu M Madan

信号转导

发表日期：2020

文献求助收藏

Receptor selectivity between the G proteins Gα(12) and Gα(13) is defined by a single leucine-to-isoleucine variation

G蛋白Gα(12)和Gα(13)之间的受体选择性是由单个亮氨酸到异亮氨酸的变异决定的。

期刊:FASEB Journal

影响因子:4.2

doi:10.1096/fj.201801956R

Mackenzie, Amanda E; Quon, Tezz; Lin, Li-Chiung; Hauser, Alexander S; Jenkins, Laura; Inoue, Asuka; Tobin, Andrew B; Gloriam, David E; Hudson, Brian D; Milligan, Graeme

信号转导

发表日期：2019

文献求助收藏

G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular disease

G蛋白偶联受体35：炎症和心血管疾病的新兴靶点

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2015.00041

Divorty, Nina; Mackenzie, Amanda E; Nicklin, Stuart A; Milligan, Graeme

G-Protein-Coupled Receptor 35 Mediates Human Saphenous Vein Vascular Smooth Muscle Cell Migration and Endothelial Cell Proliferation

G蛋白偶联受体35介导人隐静脉血管平滑肌细胞迁移和内皮细胞增殖

期刊:Journal of Vascular Research

影响因子:2.3

doi:10.1159/000444754

McCallum, Jennifer E; Mackenzie, Amanda E; Divorty, Nina; Clarke, Carolyn; Delles, Christian; Milligan, Graeme; Nicklin, Stuart A

The pharmacology of TUG-891, a potent and selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), demonstrates both potential opportunity and possible challenges to therapeutic agonism

TUG-891 是一种强效且选择性的游离脂肪酸受体 4 (FFA4/GPR120) 激动剂，其药理学研究既展现了治疗性激动剂作用的潜在机遇，也揭示了可能面临的挑战。

期刊:Molecular Pharmacology

影响因子:3

doi:10.1124/mol.113.087783

Hudson, Brian D; Shimpukade, Bharat; Mackenzie, Amanda E; Butcher, Adrian J; Pediani, John D; Christiansen, Elisabeth; Heathcote, Helen; Tobin, Andrew B; Ulven, Trond; Milligan, Graeme

G Protein-Coupled Receptor GPR35 Suppresses Lipid Accumulation in Hepatocytes

G蛋白偶联受体GPR35抑制肝细胞中脂质的积累

Combinatorial expression of GPCR isoforms affects signalling and drug responses.

GPCR亚型的组合表达会影响信号传导和药物反应

Receptor selectivity between the G proteins Gα(12) and Gα(13) is defined by a single leucine-to-isoleucine variation

G蛋白Gα(12)和Gα(13)之间的受体选择性是由单个亮氨酸到异亮氨酸的变异决定的。

G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular disease

G蛋白偶联受体35：炎症和心血管疾病的新兴靶点

G-Protein-Coupled Receptor 35 Mediates Human Saphenous Vein Vascular Smooth Muscle Cell Migration and Endothelial Cell Proliferation

G蛋白偶联受体35介导人隐静脉血管平滑肌细胞迁移和内皮细胞增殖

The pharmacology of TUG-891, a potent and selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), demonstrates both potential opportunity and possible challenges to therapeutic agonism

TUG-891 是一种强效且选择性的游离脂肪酸受体 4 (FFA4/GPR120) 激动剂，其药理学研究既展现了治疗性激动剂作用的潜在机遇，也揭示了可能面临的挑战。