日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Novel Immunocompetent Eµ-SOX11CCND1 Mouse Model Phenotypically and Molecularly Resembles Human Mantle Cell Lymphoma

新型免疫活性 Eµ-SOX11CCND1 小鼠模型在表型和分子水平上与人类套细胞淋巴瘤相似

Hedieh Jafari # ,Fiona Brown-Burke # ,Betsy Pray ,Shelby Sloan ,JoBeth Helmig-Mason ,Ian Hout ,Sydney Leon ,Mackenzie Long ,Wing Keung Chan ,Walter Hanel ,Kara Corps ,Violetta V Leshchenko ,Donna Edwards ,Ravi Prakash Shukla ,Sidorela Reci ,Kris Vaddi ,Peggy Scherle ,Paul Collier ,Alessandro La Ferlita ,Satishkumar Singh ,Rosario Distefano ,Rosa Lapalombella ,Lalit Sehgal ,Robert B Faryabi ,Cem Meydan ,Christopher E Mason ,Robert A Baiocchi # ,Samir Parekh # ,Lapo Alinari #

PRMT5 supports multiple oncogenic pathways in mantle cell lymphoma

PRMT5 支持套细胞淋巴瘤中的多种致癌途径

Shelby L Sloan, Fiona Brown, Mackenzie Long, Christoph Weigel, Shirsha Koirala, Ji-Hyun Chung, Betsy Pray, Lynda Villagomez, Claire Hinterschied, Anuvrat Sircar, JoBeth Helmig-Mason, Alexander Prouty, Eric Brooks, Youssef Youssef, Walter Hanel, Samir Parekh, Wing Keung Chan, Zhengming Chen, Rosa Lap

PRMT5 inhibition drives therapeutic vulnerability to combination treatment with BCL-2 inhibition in mantle cell lymphoma

PRMT5 抑制导致套细胞淋巴瘤对 BCL-2 抑制联合治疗的治疗脆弱性

Fiona Brown-Burke, Inah Hwang, Shelby Sloan, Claire Hinterschied, JoBeth Helmig-Mason, Mackenzie Long, Wing Keung Chan, Alexander Prouty, Ji-Hyun Chung, Yang Zhang, Satishkumar Singh, Youssef Youssef, Neha Bhagwat, Zhengming Chen, Selina Chen-Kiang, Maurizio Di Liberto, Olivier Elemento, Lalit Sehga

Validation of protein arginine methyltransferase 5 (PRMT5) as a candidate therapeutic target in the spontaneous canine model of non-Hodgkin lymphoma

验证蛋白质精氨酸甲基转移酶 5 (PRMT5) 作为非霍奇金淋巴瘤自发犬模型的候选治疗靶点

Shelby L Sloan, Kyle A Renaldo, Mackenzie Long, Ji-Hyun Chung, Lindsay E Courtney, Konstantin Shilo, Youssef Youssef, Sarah Schlotter, Fiona Brown, Brett G Klamer, Xiaoli Zhang, Ayse S Yilmaz, Hatice G Ozer, Victor E Valli, Kris Vaddi, Peggy Scherle, Lapo Alinari, William C Kisseberth, Robert A Baio