日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The aged amygdala's unique sensitivity to refined diets, independent of fat or sugar content: A brain region and cell type-specific analysis

老年杏仁核对精制饮食的独特敏感性,与脂肪或糖含量无关:一项针对特定脑区和细胞类型的分析

Butler, Michael J; Blackwell, Jade A; Sanchez, Andrew A; Sanders, Hannah F; Kolonay, Dominic W; Jantsch, Jeferson; Muscat, Stephanie M; Caetano-Silva, Maria Elisa; Shrestha, Akriti; Yun Lim, Casey Kin; Mackey-Alfonso, Sabrina E; Alvarez, Bryan D; McCusker, Robert H; Allen, Jacob M; Baskin, Kedryn K; Barrientos, Ruth M

Disruption of hippocampal mitochondrial function underlies opioid-induced postoperative cognitive dysfunction in aged rats

老年大鼠阿片类药物诱发的术后认知功能障碍的根本原因是海马线粒体功能紊乱。

Muscat, Stephanie M; Deems, Nicholas P; Alvarez, Bryan D; Butler, Michael J; Gonzalez Olmo, Brigitte M; Kolonay, Dominic W; Sanders, Hannah F; Scaria, Emmanuel A; Mackey-Alfonso, Sabrina E; Blackwell, Jade A; DeMarsh, James W; Bettes, Menaz N; Quach, Tam T; Cortese, Giuseppe P; Glasper, Erica R; Leuner, Benedetta; Baskin, Kedryn K; Barrientos, Ruth M

Neuroinflammatory mechanisms linking high-fat diets to Alzheimer's disease vulnerability: Beyond the amyloid hypothesis

高脂饮食与阿尔茨海默病易感性之间的神经炎症机制:超越淀粉样蛋白假说

Mackey-Alfonso, Sabrina E; Barrientos, Ruth M

Obesity-associated memory impairment and neuroinflammation precede widespread peripheral perturbations in aged rats

肥胖相关的记忆障碍和神经炎症先于老年大鼠广泛的外周紊乱出现。

Butler, Michael J; Muscat, Stephanie M; Caetano-Silva, Maria Elisa; Shrestha, Akriti; Olmo, Brigitte M González; Mackey-Alfonso, Sabrina E; Massa, Nashali; Alvarez, Bryan D; Blackwell, Jade A; Bettes, Menaz N; DeMarsh, James W; McCusker, Robert H; Allen, Jacob M; Barrientos, Ruth M

Ligature-induced periodontitis in a transgenic mouse model of Alzheimer's disease dysregulates neuroinflammation, exacerbates cognitive impairment, and accelerates amyloid pathology.

在阿尔茨海默病转基因小鼠模型中,结扎诱导的牙周炎会扰乱神经炎症,加剧认知障碍,并加速淀粉样蛋白病理的发生

Jimenez-Harrison Daniela M, Butler Michael J, Ijaz Haanya, Alsabbagh Rami, Bettes Menaz N, DeMarsh James W, Mackey-Alfonso Sabrina E, Muscat Stephanie M, Alvarez Bryan D, Blackwell Jade A, Taylor Ashton, Jantsch Jeferson, Sanchez Andrew A, Peters Sarah B, Barrientos Ruth M

Short-term high fat diet impairs memory, exacerbates the neuroimmune response, and evokes synaptic degradation via a complement-dependent mechanism in a mouse model of Alzheimer's disease.

短期高脂肪饮食会损害记忆力,加剧神经免疫反应,并通过补体依赖机制在阿尔茨海默病小鼠模型中引发突触退化。

Mackey-Alfonso Sabrina E, Butler Michael J, Taylor Ashton M, Williams-Medina Alberto R, Muscat Stephanie M, Fu Hongjun, Barrientos Ruth M

CD8+ T cells contribute to diet-induced memory deficits in aged male rats

CD8+ T细胞在老年雄性大鼠的饮食诱导性记忆缺陷中发挥作用

Michael J Butler ,Shouvonik Sengupta ,Stephanie M Muscat ,Stephanie A Amici ,Rebecca G Biltz ,Nicholas P Deems ,Piyush Dravid ,Sabrina Mackey-Alfonso ,Haanya Ijaz ,Menaz N Bettes ,Jonathan P Godbout ,Amit Kapoor ,Mireia Guerau-de-Arellano ,Ruth M Barrientos

Dietary fatty acids differentially impact phagocytosis, inflammatory gene expression, and mitochondrial respiration in microglial and neuronal cell models

膳食脂肪酸对小胶质细胞和神经元细胞模型中的吞噬作用、炎症基因表达和线粒体呼吸有不同的影响

Michael J Butler, Sabrina E Mackey-Alfonso, Nashali Massa, Kedryn K Baskin, Ruth M Barrientos

Young adult and aged female rats are vulnerable to amygdala-dependent, but not hippocampus-dependent, memory impairment following short-term high-fat diet

短期高脂饮食后,年轻和老年雌性大鼠容易出现依赖杏仁核而非海马体的记忆障碍

Stephanie M Muscat, Michael J Butler, Sabrina E Mackey-Alfonso, Ruth M Barrientos

Neurodegenerative Diseases: From Dysproteostasis, Altered Calcium Signalosome to Selective Neuronal Vulnerability to AAV-Mediated Gene Therapy

神经退行性疾病:从蛋白质稳态失调、钙信号体改变到神经元对腺相关病毒介导的基因治疗的选择性易感性

Quach, Tam T; Stratton, Harrison J; Khanna, Rajesh; Mackey-Alfonso, Sabrina; Deems, Nicolas; Honnorat, Jérome; Meyer, Kathrin; Duchemin, Anne-Marie