日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Perinatal cannabidiol exposure reshapes astrocyte morphology and tripartite synapse organization in a sex-dependent manner

围产期大麻二酚暴露以性别依赖的方式重塑星形胶质细胞形态和三方突触组织。

期刊:
影响因子:
doi:10.64898/2026.04.16.719010
Dias de Abreu, Gabriel Henrique; Wilson, Jeremy; Ritzmann, Vitor; Moosbrugger, Oscar; Johnson, Clare T; Mackie, Ken; Bradshaw, Heather; Huang, Jui-Yen; Lu, Hui-Chen
细胞生物学
胶质细胞
神经科学
发表日期：2026
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Vascular network-inspired diffusible scaffolds for engineering functional midbrain organoids.

受血管网络启发的可扩散支架，用于构建功能性中脑类器官

期刊:Cell Stem Cell
影响因子:20.4
doi:10.1016/j.stem.2025.02.010
Cai Hongwei, Tian Chunhui, Chen Lei, Yang Yang, Sun Alfred Xuyang, McCracken Kyle, Tchieu Jason, Gu Mingxia, Mackie Ken, Guo Feng
心血管
发表日期：2025
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Acetaminophen inhibits diacylglycerol lipase synthesis of 2-arachidonoyl glycerol: Implications for nociception

对乙酰氨基酚抑制二酰甘油脂肪酶合成2-花生四烯酸甘油酯：对伤害感受的影响

期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2025.102139
Dvorakova, Michaela; Bosquez-Berger, Taryn; Billingsley, Jenna; Murataeva, Natalia; Woodward, Taylor; Leishman, Emma; Zimmowitch, Anaëlle; Gibson, Anne; Wager-Miller, Jim; Cai, Ruyi; Cai, Shangxuan; Ware, Tim; Hsu, Ku-Lung; Li, Yulong; Bradshaw, Heather; Mackie, Ken; Straiker, Alex
发表日期：2025
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CB(1) cannabinoid receptor agonists induce acute respiratory depression in awake mice

CB(1)大麻素受体激动剂可诱导清醒小鼠发生急性呼吸抑制

期刊:Pharmacological Research
影响因子:10.5
doi:10.1016/j.phrs.2025.107682
Watkins, Joshua; Aradi, Petra; Hahn, Rachel; Makriyannis, Alexandros; Mackie, Ken; Katona, Istvan; Hohmann, Andrea G
信号转导
发表日期：2025
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Mice lacking the endocannabinoid-synthesizing enzyme NAPE-PLD exhibit sex-dependent dysregulations in responsiveness to oxycodone and a natural reward

缺乏内源性大麻素合成酶NAPE-PLD的小鼠对羟考酮和自然奖励的反应存在性别依赖性失调。

期刊:Neuropharmacology
影响因子:4.6
doi:10.1016/j.neuropharm.2025.110573
Woodward, Taylor J; Sizemore, Emily; Balaji, Ananya; Port, Ada; Hainline, John; Kazi, Hasaan; Luquet, Serge; Mackie, Ken; Hohmann, Andrea G
发表日期：2025
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Genetic deletion of NAPE-PLD alters stress responsiveness and HPA-axis functionality in a context-dependent manner in mice.

NAPE-PLD 基因缺失会以依赖于环境的方式改变小鼠的应激反应和 HPA 轴功能。

期刊:Neuropharmacology
影响因子:4.6
doi:10.1016/j.neuropharm.2025.110702
Woodward Taylor J, Dimen Diana, Sizemore Emily Fender, Stockman Sarah, Kazi Fezaan, Luquet Serge, Mackie Ken, Katona Istvan, Hohmann Andrea G
发表日期：2025
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Reelin Deficiency and Synaptic Impairment in the Adolescent Prefrontal Cortex Following Initial Synthetic Cannabinoid Exposure

青少年首次接触合成大麻素后前额叶皮层中Reelin蛋白缺乏和突触功能障碍

期刊:Biological Psychiatry: Global Open Science
影响因子:3.7
doi:10.1016/j.bpsgos.2024.100426
Silva-Hurtado, Thenzing J; Giua, Gabriele; Lassalle, Olivier; Makrini-Maleville, Leila; Strauss, Benjamin; Wager-Miller, Jim; Freyermuth, Jean-Marc; Mackie, Ken; Valjent, Emmanuel; Manzoni, Olivier J J; Chavis, Pascale
Reelin
神经科学
发表日期：2025
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Deletion of Endocannabinoid Synthesizing Enzyme DAGLα in Pcp2-Positive Cerebellar Purkinje Cells Decreases Depolarization-Induced Short-Term Synaptic Plasticity, Reduces Social Preference, and Heightens Anxiety.

缺失 Pcp2 阳性小脑浦肯野细胞中的内源性大麻素合成酶 DAGLα 会降低去极化诱导的短期突触可塑性，降低社交偏好，并加剧焦虑

期刊:eNeuro
影响因子:2.7
doi:10.1523/ENEURO.0400-24.2025
Smith Gabriella, McCoy Kathleen, Di Prisco Gonzalo Viana, Kuklish Alexander, Grant Emma, Bhat Mayil, Patel Sachin, Mackie Ken, Atwood Brady, Kalinovsky Anna
细胞生物学
发表日期：2025
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CB1 and CB2 receptors differentially modulate the cognitive impact of maternal immune activation and perinatal cannabinoid exposure

CB1 和 CB2 受体对母体免疫激活和围产期大麻素暴露的认知影响具有不同的调节作用

期刊:Behavioural Brain Research
影响因子:2.3
doi:10.1016/j.bbr.2025.115543
Chen, Han-Ting; Mackie, Ken
信号转导
神经科学
免疫/内分泌
发表日期：2025
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Human brain organoids for understanding substance use disorders

用于了解物质使用障碍的人类脑类器官

期刊:Drug Metabolism and Pharmacokinetics
影响因子:2.2
doi:10.1016/j.dmpk.2024.101036
Li, Kangle; Gu, Longjun; Cai, Hongwei; Lu, Hui-Chen; Mackie, Ken; Guo, Feng
3D/类器官
Human
神经科学
发表日期：2025
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