BOXR1030, an anti-GPC3 CAR with exogenous GOT2 expression, shows enhanced T cell metabolism and improved anti-cell line derived tumor xenograft activity
BOXR1030 是一种具有外源性 GOT2 表达的抗 GPC3 CAR，表现出增强的 T 细胞代谢和增强的抗细胞系衍生肿瘤异种移植活性
期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0266980
Taylor L Hickman, Eugene Choi, Kathleen R Whiteman, Sujatha Muralidharan, Tapasya Pai, Tyler Johnson, Avani Parikh, Taylor Friedman, Madaline Gilbert, Binzhang Shen, Luke Barron, Kathleen E McGinness, Seth A Ettenberg, Greg T Motz, Glen J Weiss, Amy Jensen-Smith
代谢
肿瘤
T细胞
Functional/Block/Neutralize
CD3E
