A novel drug prejudice scaffold-imidazopyridine-conjugate can promote cell death in a colorectal cancer model by binding to β-catenin and suppressing the Wnt signaling pathway
一种新型药物靶向支架——咪唑并吡啶缀合物，可通过与β-catenin结合并抑制Wnt信号通路，促进结直肠癌模型中的细胞死亡。
期刊:Journal of Advanced Research
影响因子:13
doi:10.1016/j.jare.2024.07.022
Yang, Min Hee; Basappa, Basappa; Deveshegowda, Suresha N; Ravish, Akshay; Mohan, Arunkumar; Nagaraja, Omantheswara; Madegowda, Mahendra; Rangappa, Kanchugarakoppal S; Deivasigamani, Amudha; Pandey, Vijay; Lobie, Peter E; Hui, Kam Man; Sethi, Gautam; Ahn, Kwang Seok
肿瘤
肠癌
肿瘤免疫
信号转导
Wnt/β-Catenin
细胞生物学
