Drug repurposing screen identifies an HRI activating compound that promotes adaptive mitochondrial remodeling in MFN2-deficient cells.
药物再利用筛选发现了一种 HRI 激活化合物，该化合物可促进 MFN2 缺陷细胞中的线粒体适应性重塑。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2517552122
Bora Prerona, Zaman Mashiat, Oviedo Samantha, Kutseikin Sergei, Madrazo Nicole, Mathur Prakhyat, Pannikkat Meera, Krasny Sophia, Aldakhlallah Rama, Chu Alan, Johnson Kristen A, Grotjahn Danielle A, Shutt Timothy E, Wiseman R Luke
