日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Systematic metabolite screening identifies functional regulators of the adenosine A2A receptor

系统性代谢物筛选鉴定出腺苷A2A受体的功能调节因子

Rao, Prashant; Rathinaswamy, Manoj; Chan, Michelle; Paredes, Andrea Guzmán; Patel, Chirag; Wranik, Bernd J; Powell, Jonathan; Eaton, Dan; Rutter, Jared; Hicks, Kevin G; Mafi, Amirhossein; Hao, Qi

Structural basis of MPL activation by thrombopoietin

血小板生成素激活MPL的结构基础

Mafi, Amirhossein; Bratkowski, Matthew; Geng, Jiefei; Brito, Alyssa A; Sridar, Janani; Hu, Dongjian; Darcy, Anhdao T; Nanavati, Dhaval; Brown, Nathan J; Rathinaswamy, Manoj K; Kutskova, Yuliya; Eaton, Dan; Hao, Qi; Paddock, Marcia

Discovery of reactive peptide inhibitors of human papillomavirus oncoprotein E6

发现人乳头瘤病毒癌蛋白E6的反应性肽抑制剂

Ye, Xiyun; Zhang, Peiyuan; Tao, Jason; Wang, John C K; Mafi, Amirhossein; Grob, Nathalie M; Quartararo, Anthony J; Baddock, Hannah T; Chan, Leanne J G; McAllister, Fiona E; Foe, Ian; Loas, Andrei; Eaton, Dan L; Hao, Qi; Nile, Aaron H; Pentelute, Bradley L

Correction to: Novel interaction between neurotrophic factor-α1/carboxypeptidase E and serotonin receptor, 5-HTR1E, protects human neurons against oxidative/neuroexcitotoxic stress via β-arrestin/ERK signaling

更正:神经营养因子-α1/羧肽酶E与血清素受体5-HTR1E之间的新型相互作用通过β-arrestin/ERK信号通路保护人类神经元免受氧化/神经兴奋性毒性应激

Sharma, Vinay Kumar; Yang, Xuyu; Kim, Soo-Kyung; Mafi, Amirhossein; Saiz-Sanchez, Daniel; Villanueva-Anguita, Patricia; Xiao, Lan; Inoue, Asuka; Goddard, William A 3rd; Loh, Y Peng; Toulabi, Leila

The mechanism for ligand activation of the GPCR-G protein complex

GPCR-G蛋白复合物配体激活的机制

Mafi, Amirhossein; Kim, Soo-Kyung; Goddard, William A 3rd

Identification and characterization of an atypical Gαs-biased β(2)AR agonist that fails to evoke airway smooth muscle cell tachyphylaxis

鉴定和表征一种非典型Gαs偏向性β(2)肾上腺素能受体激动剂,该激动剂无法诱发气道平滑肌细胞快速耐受性

Kim, Donghwa; Tokmakova, Alina; Lujan, Lauren K; Strzelinski, Hannah R; Kim, Nicholas; Najari Beidokhti, Maliheh; Giulianotti, Marc A; Mafi, Amirhossein; Woo, Jung-A A; An, Steven S; Goddard, William A 3rd; Liggett, Stephen B

Predicted structure of fully activated human bitter taste receptor TAS2R4 complexed with G protein and agonists

预测的完全激活的人类苦味受体TAS2R4与G蛋白和激动剂的复合物结构

Yang, Moon Young; Mafi, Amirhossein; Kim, Soo-Kyung; Goddard, William A 3rd; Guthrie, Brian

The G protein-first activation mechanism of opioid receptors by Gi protein and agonists.

Gi蛋白和激动剂激活阿片受体的G蛋白优先激活机制

Mafi Amirhossein, Kim Soo-Kyung, Goddard William A 3rd

Mechanism of β-arrestin recruitment by the μ-opioid G protein-coupled receptor

μ-阿片类G蛋白偶联受体募集β-arrestin的机制

Mafi, Amirhossein; Kim, Soo-Kyung; Goddard, William A 3rd

The atomistic level structure for the activated human κ-opioid receptor bound to the full Gi protein and the MP1104 agonist

活化的人类κ-阿片受体与完整Gi蛋白和MP1104激动剂结合的原子级结构

Mafi, Amirhossein; Kim, Soo-Kyung; Goddard, William A 3rd