日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural determination of small proteins by cryo-EM using a coiled coil module strategy

利用螺旋线圈模块策略通过冷冻电镜进行小蛋白结构测定

Camille, Samson; Irène, Dossou; Anke, Steinmetz; Anand, Kumar; Magali, Mathieu; Alexey, Rak

Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold

使用深度突变表位图谱和 AlphaFold 解释 LAMP-1 抗体的跨物种反应性

Tiphanie Pruvost, Magali Mathieu, Steven Dubois, Bernard Maillère, Emmanuelle Vigne, Hervé Nozach

Structural insights into the bi-specific cross-over dual variable antibody architecture by cryo-EM

通过低温电子显微镜深入了解双特异性交叉双变量抗体结构

David Fernandez-Martinez, Mark D Tully, Gordon Leonard, Magali Mathieu, Eaazhisai Kandiah

Aberrant expression of transglutaminase 2 in pancreas and thymus of NOD mice underscores the importance of deamidation in neoantigen generation

NOD小鼠胰腺和胸腺中转谷氨酰胺酶2的异常表达凸显了脱酰胺作用在新抗原生成中的重要性。

Callebaut, Aїsha; Bruggeman, Ylke; Zamit, Cloé; Sodré, Fernanda Marques Câmara; Irla, Magali; Mathieu, Chantal; Buitinga, Mijke; Overbergh, Lut

KRAS G12C fragment screening renders new binding pockets

KRAS G12C 片段筛选产生新的结合口袋

Magali Mathieu, Valérie Steier, Florence Fassy, Cécile Delorme, David Papin, Bruno Genet, Francis Duffieux, Thomas Bertrand, Laure Delarbre, Hélène Le-Borgne, Annick Parent, Patrick Didier, Jean-Pierre Marquette, Maryse Lowinski, Jacques Houtmann, Annabelle Lamberton, Laurent Debussche, Rak Alexey

An end-to-end automated platform process for high-throughput engineering of next-generation multi-specific antibody therapeutics

用于下一代多特异性抗体疗法高通量工程的端到端自动化平台流程

Norbert Furtmann, Marion Schneider, Nadja Spindler, Bjoern Steinmann, Ziyu Li, Ingo Focken, Joachim Meyer, Dilyana Dimova, Katja Kroll, Wulf Dirk Leuschner, Audrey Debeaumont, Magali Mathieu, Christian Lange, Werner Dittrich, Jochen Kruip, Thorsten Schmidt, Joerg Birkenfeld

Genetic Diversity and Phylogeny of Aedes aegypti, the Main Arbovirus Vector in the Pacific

太平洋地区主要虫媒病毒媒介埃及伊蚊的遗传多样性和系统发育

Calvez, Elodie; Guillaumot, Laurent; Millet, Laurent; Marie, Jérôme; Bossin, Hervé; Rama, Vineshwaran; Faamoe, Akata; Kilama, Sosiasi; Teurlai, Magali; Mathieu-Daudé, Françoise; Dupont-Rouzeyrol, Myrielle

Automated harvesting and processing of protein crystals through laser photoablation

通过激光光烧蚀自动收获和处理蛋白质晶体

Ulrich Zander, Guillaume Hoffmann, Irina Cornaciu, Jean-Pierre Marquette, Gergely Papp, Christophe Landret, Gaël Seroul, Jérémy Sinoir, Martin Röwer, Frank Felisaz, Sonia Rodriguez-Puente, Vincent Mariaule, Peter Murphy, Magali Mathieu, Florent Cipriani, José Antonio Márquez

Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule

通过变构小分子破坏金属结合网络选择性抑制突变异柠檬酸脱氢酶 1 (IDH1)

Gejing Deng, Junqing Shen, Ming Yin, Jessica McManus, Magali Mathieu, Patricia Gee, Timothy He, Chaomei Shi, Olivier Bedel, Larry R McLean, Frank Le-Strat, Ying Zhang, Jean-Pierre Marquette, Qiang Gao, Bailin Zhang, Alexey Rak, Dietmar Hoffmann, Eamonn Rooney, Aurelie Vassort, Walter Englaro, Yi Li,

Structures of a pan-specific antagonist antibody complexed to different isoforms of TGFβ reveal structural plasticity of antibody-antigen interactions

与 TGFβ 不同亚型复合的泛特异性拮抗抗体的结构揭示了抗体-抗原相互作用的结构可塑性

Aaron Moulin, Magali Mathieu, Catherine Lawrence, Russell Bigelow, Mark Levine, Christine Hamel, Jean-Piere Marquette, Josiane Le Parc, Christophe Loux, Paul Ferrari, Cecile Capdevila, Jacques Dumas, Bruno Dumas, Alexey Rak, Julie Bird, Huawei Qiu, Clark Q Pan, Tim Edmunds, Ronnie R Wei