日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Safety, Immunogenicity, and Vaccine Compatibility of a Trivalent Inactivated In Ovo Nanovaccine Against Avian Colibacillosis in Broilers Under Commercial Hatchery Conditions

在商业孵化场条件下，针对肉鸡禽大肠杆菌病的三价卵内灭活纳米疫苗的安全性、免疫原性和疫苗相容性

期刊:Animals
影响因子:2.7
doi:10.3390/ani16060931
Scuotto, Angelo; Ogonczyk-Makowska, Daniela; Magnez, Romain; Thiroux, Bryan; Herrouin, Pierre-Louis; Bouillet, Thomas; Vreulx, Anaïs-Camille; Degraeve, Amélie; Betbeder, Didier
免疫/内分泌
发表日期：2026
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Novel PD-L1-Targeted Phenyl-Pyrazolone Derivatives with Antioxidant Properties

具有抗氧化特性的新型 PD-L1 靶向苯基吡唑酮衍生物

期刊:Molecules
影响因子:4.2
doi:10.3390/molecules28083491
Romain Regnault, Frédérique Klupsch, Hassiba El-Bouazzati, Romain Magnez, Raphaël Le Biannic, Natascha Leleu-Chavain, Hania Ahouari, Hervé Vezin, Régis Millet, Jean-François Goossens, Xavier Thuru, Christian Bailly
信号转导
发表日期：2023
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A Potential Off-Target Effect of the Wnt/β-Catenin Inhibitor KYA1797K: PD-L1 Binding and Checkpoint Inhibition.

Wnt/β-catenin抑制剂KYA1797K的潜在脱靶效应：PD-L1结合和检查点抑制

期刊:Biomedicine Hub
影响因子:
doi:10.1159/000528499
Thuru Xavier, Magnez Romain, Vergoten Gérard, Bailly Christian
信号转导
Wnt/β-Catenin
发表日期：2023
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IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein

IL-2 在肿瘤的酸性 pH 环境中失活，因此可以设计出 pH 选择性突变蛋白

期刊:Science Immunology
影响因子:17.6
doi:10.1126/sciimmunol.ade5686
Silvia Gaggero, Jonathan Martinez-Fabregas, Adeline Cozzani, Paul K Fyfe, Malo Leprohon, Jie Yang, F Emil Thomasen, Hauke Winkelmann, Romain Magnez, Alberto G Conti, Stephan Wilmes, Elizabeth Pohler, Manuel van Gijsel Bonnello, Xavier Thuru, Bruno Quesnel, Fabrice Soncin, Jacob Piehler, Kresten Lind
肿瘤
Cell sorting
FCM
发表日期：2022
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Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells

TrkA/CD44v3 的直接相互作用对于 NGF 促进乳腺癌细胞的侵袭性至关重要

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:11.4
doi:10.1186/s13046-022-02314-4
Sarah Trouvilliez #, Julien Cicero #, Romain Lévêque, Léo Aubert, Cyril Corbet, Alexandre Van Outryve, Karolin Streule, Pierre-Olivier Angrand, Pamela Völkel, Romain Magnez, Guillaume Brysbaert, Caroline Mysiorek, Fabien Gosselet, Roland Bourette, Eric Adriaenssens, Xavier Thuru, Chann Lagadec, Jérô
肿瘤
乳腺癌
肿瘤细胞
发表日期：2022
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Pyrazolones as inhibitors of immune checkpoint blocking the PD-1/PD-L1 interaction

吡唑酮类药物作为免疫检查点抑制剂阻断 PD-1/PD-L1 相互作用

期刊:European Journal of Medicinal Chemistry
影响因子:6
doi:10.1016/j.ejmech.2022.114343
Raphaël Le Biannic, Romain Magnez, Frédérique Klupsch, Natascha Leleu-Chavain, Bryan Thiroux, Morgane Tardy, Hassiba El Bouazzati, Xavier Dezitter, Nicolas Renault, Gérard Vergoten, Christian Bailly, Bruno Quesnel, Xavier Thuru, Régis Millet
免疫
发表日期：2022
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A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively

LRRK2磷酸化位点突变方法将磷酸化和去磷酸化分别与保护性和有害性标记联系起来

期刊:Cells
影响因子:5.2
doi:10.3390/cells11061018
Marchand, Antoine; Sarchione, Alessia; Athanasopoulos, Panagiotis S; Roy, Hélène Bauderlique-Le; Goveas, Liesel; Magnez, Romain; Drouyer, Matthieu; Emanuele, Marco; Ho, Franz Y; Liberelle, Maxime; Melnyk, Patricia; Lebègue, Nicolas; Thuru, Xavier; Nichols, R Jeremy; Greggio, Elisa; Kortholt, Arjan; Galli, Thierry; Chartier-Harlin, Marie-Christine; Taymans, Jean-Marc
信号转导
磷酸化
LRRK2
发表日期：2022
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Microscale Thermophoresis as a Tool to Study Protein Interactions and Their Implication in Human Diseases

利用微尺度热泳技术研究蛋白质相互作用及其在人类疾病中的作用

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms23147672
Magnez, Romain; Bailly, Christian; Thuru, Xavier
Human
发表日期：2022
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Antioxidant Properties and Aldehyde Reactivity of PD-L1 Targeted Aryl-Pyrazolone Anticancer Agents

PD-L1靶向芳基吡唑酮类抗癌药物的抗氧化特性和醛反应性

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules27103316
Leleu-Chavain, Natascha; Regnault, Romain; Ahouari, Hania; Le Biannic, Raphaël; Kouach, Mostafa; Klupsch, Frédérique; Magnez, Romain; Vezin, Hervé; Thuru, Xavier; Bailly, Christian; Goossens, Jean-François; Millet, Régis
PD-L1
肿瘤
肿瘤免疫
发表日期：2022
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Drug Repurposing to Enhance Antitumor Response to PD-1/PD-L1 Immune Checkpoint Inhibitors

药物再利用增强PD-1/PD-L1免疫检查点抑制剂的抗肿瘤反应

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers14143368
Thuru, Xavier; Magnez, Romain; El-Bouazzati, Hassiba; Vergoten, Gérard; Quesnel, Bruno; Bailly, Christian
Checkpoint
肿瘤
肿瘤免疫
PD-L1
PD-1
免疫/内分泌
发表日期：2022
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