Spatial colocalization and combined survival benefit of natural killer and CD8 T cells despite profound MHC class I loss in non-small cell lung cancer
在非小细胞肺癌中,尽管MHC I类分子严重缺失,自然杀伤细胞和CD8 T细胞仍存在空间共定位并共同发挥生存优势。
期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2024-009126
Wessel, Remziye E; Ageeb, Nardin; Obeid, Joseph M; Mauldin, Ileana S; Goundry, Kate A; Hanson, Gabriel F; Hossain, Mahdin; Lehman, Chad; Gentzler, Ryan D; Wages, Nolan A; Slingluff, Craig L Jr; Bullock, Timothy N J; Dolatshahi, Sepideh; Brown, Michael G
肺癌
T细胞
细胞生物学
肿瘤免疫
肿瘤
自然杀伤细胞
T细胞
CD8
免疫/内分泌