日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Intranasal Human NSC-Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS-STING Signalling, in Aged Hippocampus

鼻内给予人神经干细胞来源的细胞外囊泡疗法可以抑制老年海马体中炎症性小胶质细胞的转录组以及NLRP3和cGAS-STING信号通路

期刊:Journal of Extracellular Vesicles
影响因子:14.5
doi:10.1002/jev2.70232
Madhu, Leelavathi N; Kodali, Maheedhar; Rao, Shama; Attaluri, Sahithi; Upadhya, Raghavendra; Shankar, Goutham; Shuai, Bing; Somayaji, Yogish; Ganesh, Shruthi V; Kumar, Vignesh S; James, Jeswin E; Shetty, Padmashri A; LeMaire, Avery; Rao, Xiaolan; Cai, James J; Shetty, Ashok K
胶质细胞
发育与干细胞
炎症
炎症/感染
信号转导
STING
cGAS-STING
LRP3
Human
干细胞
NLRP3
囊泡
细胞生物学
Hippo
发表日期：2026
文献求助 收藏

Intranasal Human NSC-Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS-STING Signaling, in Aged Hippocampus

鼻内给予人神经干细胞来源的细胞外囊泡疗法可以抑制老年海马体中炎症性小胶质细胞的转录组以及NLRP3和cGAS-STING信号通路

期刊:
影响因子:
doi:10.1101/2025.03.02.641082
Madhu, Leelavathi N; Kodali, Maheedhar; Rao, Shama; Attaluri, Sahithi; Upadhya, Raghavendra; Shankar, Goutham; Shuai, Bing; Somayaji, Yogish; Ganesh, Shruthi V; Kumar, Vignesh S; James, Jeswin E; Shetty, Padmashri; LeMaire, Avery; Rao, Xiaolan; Cai, James J; Shetty, Ashok K
胶质细胞
发育与干细胞
炎症
炎症/感染
信号转导
STING
cGAS-STING
LRP3
Human
干细胞
NLRP3
囊泡
细胞生物学
Hippo
发表日期：2026
文献求助 收藏

Transcriptomic and epigenetic analysis of various cell types affected by amyloid‐beta oligomers in the hippocampus of mice during aging

对衰老小鼠海马中受β-淀粉样蛋白寡聚体影响的各种细胞类型的转录组学和表观遗传学分析

期刊:Aging Cell
影响因子:7.1
doi:10.1111/acel.14398
Kodali, Maheedhar; Madhu, Leelavathi N; Somayaji, Yogish; Attaluri, Sahithi; Huard, Charles; Panda, Prashanta Kumar; Shankar, Goutham; Rao, Shama; Shuai, Bing; Gonzalez, Jenny J; Oake, Chris; Hering, Catherine; Babu, Roshni Sara; Kotian, Sanya; Shetty, Ashok K; Leduc, Klarissa
细胞生物学
衰老
表观遗传
发表日期：2025
文献求助 收藏

Corrigendum: Brain-specific increase in leukotriene signaling accompanies chronic neuroinflammation and cognitive impairment in a model of Gulf War Illness

更正：在海湾战争综合征模型中，脑特异性白三烯信号传导增加伴随慢性神经炎症和认知障碍。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1557065
Attaluri, Sahithi; Upadhya, Raghavendra; Kodali, Maheedhar; Madhu, Leelavathi N; Upadhya, Dinesh; Shuai, Bing; Shetty, Ashok K
炎症
炎症/感染
信号转导
神经科学
神经炎症
发表日期：2025
文献求助 收藏

Microglia-Mediated Neuroinflammation Through Phosphatidylinositol 3-Kinase Signaling Causes Cognitive Dysfunction

小胶质细胞通过磷脂酰肌醇3-激酶信号通路介导的神经炎症导致认知功能障碍

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26157212
Maziz, Mohammad Nazmul Hasan; Chakravarthi, Srikumar; Aung, Thidar; Htoo, Phone Myint; Shwe, Wana Hla; Gupalo, Sergey; Udayah, Manglesh Waran; Singh, Hardev; Kabir, Mohammed Shahjahan; Thangarajan, Rajesh; Kodali, Maheedhar
胶质细胞
炎症
炎症/感染
信号转导
神经科学
细胞生物学
神经炎症
发表日期：2025
文献求助 收藏

Intranasal delivery of metformin using metal-organic framework (MOF)-74-Mg nanocarriers.

利用金属有机框架（MOF）-74-Mg纳米载体进行二甲双胍的鼻内递送

期刊:Advanced Composites and Hybrid Materials
影响因子:
doi:10.1007/s42114-025-01227-y
Yuan Muzhaozi, Han Zongsu, Somayaji Yogish, Nguyen Nguyen, Hu Hanwen, Madhu Leelavathi N, Attaluri Sahithi, Kodali Maheedhar, Yang Yihao, Hsu Yu-Chuan, Ahuja Avik, Srinivasan Rahul, Pellois Jean-Philippe, Zhou Hong-Cai, Shetty Ashok K, Wang Ya
发表日期：2025
文献求助 收藏

FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis

FDA 批准的大麻二酚 [Epidiolex®] 可缓解海湾战争综合症相关的认知和情绪功能障碍、痛觉过敏、神经炎症信号传导和神经发生减少

期刊:Military Medical Research
影响因子:16.7
doi:10.1186/s40779-024-00563-2
Maheedhar Kodali, Leelavathi N Madhu, Venkata Sai Vashishta Kolla, Sahithi Attaluri, Charles Huard, Yogish Somayaji, Bing Shuai, Chase Jordan, Xiaolan Rao, Sanath Shetty, Ashok K Shetty
神经
神经炎症
发表日期：2024
文献求助 收藏

Extracellular vesicles from human-induced pluripotent stem cell-derived neural stem cells alleviate proinflammatory cascades within disease-associated microglia in Alzheimer's disease.

人诱导多能干细胞衍生的神经干细胞产生的细胞外囊泡可减轻阿尔茨海默病中与疾病相关的小胶质细胞内的促炎级联反应

期刊:Journal of Extracellular Vesicles
影响因子:14.5
doi:10.1002/jev2.12519
Madhu Leelavathi N, Kodali Maheedhar, Upadhya Raghavendra, Rao Shama, Somayaji Yogish, Attaluri Sahithi, Shuai Bing, Kirmani Maha, Gupta Shreyan, Maness Nathaniel, Rao Xiaolan, Cai James J, Shetty Ashok K
神经科学
囊泡
发表日期：2024
文献求助 收藏

Extracellular vesicles from hiPSC-NSCs can prevent peripheral inflammation-induced cognitive dysfunction with inflammasome inhibition and improved neurogenesis in the hippocampus

hiPSC-NSC 的细胞外囊泡可通过抑制炎症小体和改善海马神经发生来预防外周炎症引起的认知功能障碍

期刊:Journal of Neuroinflammation
影响因子:9.3
doi:10.1186/s12974-023-02971-y
Gunel Ayyubova #, Maheedhar Kodali #, Raghavendra Upadhya, Leelavathi N Madhu, Sahithi Attaluri, Yogish Somayaji, Bing Shuai, Shama Rao, Goutham Shankar, Ashok K Shetty
信号转导
神经
其它细胞
炎性小体
发表日期：2023
文献求助 收藏

Intranasally administered human MSC-derived extracellular vesicles inhibit NLRP3-p38/MAPK signaling after TBI and prevent chronic brain dysfunction

鼻腔内施用人类 MSC 衍生的细胞外囊泡可抑制 TBI 后的 NLRP3-p38/MAPK 信号传导并预防慢性脑功能障碍

期刊:Brain Behavior and Immunity
影响因子:8.8
doi:10.1016/j.bbi.2022.11.014
Maheedhar Kodali, Leelavathi N Madhu, Roxanne L Reger, Bojana Milutinovic, Raghavendra Upadhya, Jenny J Gonzalez, Sahithi Attaluri, Bing Shuai, Daniel L G Gitai, Shama Rao, Jong M Choi, Sung Y Jung, Ashok K Shetty
免疫
细胞生物学
其它细胞
MAPK/ERK
发表日期：2023
文献求助 收藏