日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural stability of symmetric bispecific antibodies: a case study showing potential compromise near linker regions

对称双特异性抗体的结构稳定性:以连接区附近潜在的结构缺陷为例

Ingavat, Nattha; Kok, Yee Jiun; Dzulkiflie, Nuruljannah; Min, Liew Jia; Xinhui, Wang; Low, Kia Ngee; But, Ka Pui; Anajao, Amihan; Ping, Loh Han; Ong, Han Kee; Mahfut, Farouq Bin; Yang, Yuansheng; Bi, Xuezhi; Zhang, Wei

Comprehensive Lipidomic Analysis of Recombinant Protein-Producing CHO Cell Cultures: Insights for Media and Process Development

重组蛋白生产CHO细胞培养物的全面脂质组学分析:对培养基和工艺开发的启示

Nayak, Hemal; Beaser, Andrew D; Aziz, Zaid A; Urias, Eduardo; Ramani, Shyama V; Chen, Shuwen; Peh, Esther Kai Lay; Mahfut, Farouq Bin; Yang, Yuan Sheng; Ho, Yin Ying; Ho, Ying Swan

Comprehensive Lipidomic Analysis of Recombinant Protein-Producing CHO Cell Cultures: Insights for Media and Process Development

重组蛋白生产CHO细胞培养物的全面脂质组学分析:对培养基和工艺开发的启示

Chen, Shuwen; Peh, Esther Kai Lay; Mahfut, Farouq Bin; Yang, Yuan Sheng; Ho, Yin Ying; Ho, Ying Swan

Antibody glycan quality predicted from CHO cell culture media markers and machine learning

根据 CHO 细胞培养基标记物和机器学习预测抗体聚糖质量

Meiyappan Lakshmanan, Sean Chia, Kuin Tian Pang, Lyn Chiin Sim, Gavin Teo, Shi Ya Mak, Shuwen Chen, Hsueh Lee Lim, Alison P Lee, Farouq Bin Mahfut, Say Kong Ng, Yuansheng Yang, Annie Soh, Andy Hee-Meng Tan, Andre Choo, Ying Swan Ho, Terry Nguyen-Khuong, Ian Walsh

Manufacturability and functionality assessment of different formats of T-cell engaging bispecific antibodies

不同形式的 T 细胞接合双特异性抗体的可制造性和功能性评估

Han Ping Loh, Farouq Bin Mahfut, Serene W Chen, Yuhan Huang, Jianxin Huo, Wei Zhang, Kong Peng Lam, Shengli Xu, Yuansheng Yang

Harnessing ceramic hydroxyapatite as an effective polishing strategy to remove product- and process-related impurities in bispecific antibody purification

利用陶瓷羟基磷灰石作为有效的抛光策略,去除双特异性抗体纯化过程中与产品和工艺相关的杂质

Nattha Ingavat, Xinhui Wang, Jia Min Liew, Farouq Bin Mahfut, Ka Pui But, Yee Jiun Kok, Xuezhi Bi, Yuansheng Yang, Kobayashi Shintaro, Maria Tsoumpra, Wei Zhang

Leveraging an advanced simulated moving bed approach to achieve 3-component separation for enhanced impurity removal in a non-affinity cation exchange capture step

利用先进的模拟移动床方法,在非亲和阳离子交换捕获步骤中实现三组分分离,从而增强杂质去除效果。

Chen, Serene W; Zheng, Zi Ying; Mahfut, Farouq Bin; Yang, Yuansheng; Ogino, Masahiro; Okada, Kazuo; Sato, Kohei; Zhang, Wei

Development of a T cell-redirecting bispecific antibody targeting B-cell maturation antigen for the suppression of multiple myeloma cell growth

开发一种靶向B细胞成熟抗原的T细胞重定向双特异性抗体,用于抑制多发性骨髓瘤细胞的生长

Huo, Jianxin; Huang, Yuhan; Zheng, Ziying; Tay, Xin Ni; Mahfut, Farouq Bin; Zhang, Wei; Lam, Kong-Peng; Yang, Yuansheng; Xu, Shengli

Excellent removal of knob-into-hole bispecific antibody byproducts and impurities in a single-capture chromatography

通过单次捕获色谱法有效去除旋钮入孔双特异性抗体副产物和杂质

Serene W Chen, Kong Meng Hoi, Farouq Bin Mahfut, Yuansheng Yang, Wei Zhang

Effective flow-through polishing strategies for knob-into-hole bispecific antibodies

旋钮入孔双特异性抗体的有效流通抛光策略

Serene W Chen, Kong Meng Hoi, Farouq Bin Mahfut, Yuansheng Yang, Wei Zhang