Maikel相关文献与解析，生知库 | 链接生命科学的每一步

Human liver-derived organoids recapitulate Oropouche virus infection and manifestation, enabling antiviral drug discovery

人肝源性类器官能够重现奥罗普切病毒的感染和临床表现，从而有助于抗病毒药物的研发。

doi:10.1016/j.xcrm.2026.102646

Li, Jiajing; Wang, Xin; Ding, Yibo; Qin, Fang; de Lima, Shirlene T S; Papamichail, Lito; Schraauwen, Rick; Forato, Julia; Claro, Ingra M; Hua, Xinyi; Simões Mello, Leda M; Offermans, Dewy Mae; Verstegen, Monique M A; Boter, Marjan; Peppelenbosch, Maikel P; Barbiero, Anna; Pagani, Elisabetta; Janssen, Harry L A; Telmos Silva, José A; Dos Santos, Magnun N N; Pincinato, Eder C; Proenca-Modena, José Luiz; Li, Pengfei; Anas, Adam A; van der Laan, Luc J W; Castilletti, Concetta; Oude Munnink, Bas B; de Souza, William M; Wang, Wenshi; Pan, Qiuwei

Selective SIK2/SIK3 inhibition reprograms pro- and antiinflammatory pathways in myeloid cells, improving autoimmune disease outcomes

选择性抑制SIK2/SIK3可重编程髓系细胞中的促炎和抗炎通路，从而改善自身免疫性疾病的预后。

期刊:JCI Insight

影响因子:6.1

doi:10.1172/jci.insight.171776

De Vos, Steve; Desroy, Nicolas; Bellaire, Susan J; Fernandes, Anna Pereira; Lavazais, Stéphanie; Merciris, Didier; Delachaume, Carole; Robin-Jagerschmidt, Catherine; Cosson, Adrien; Lazaryan, Angela; Van Osselaer, Nancy; Amantini, David; Peixoto, Christophe; Colli, Maikel L; Van Eeckhoutte, Thomas; Hakonen, Tiina; Constant, Magali; Garcia-Hernandez, Alberto; Barron, Rahul; D'Haens, Geert; Böcher, Wulf O

Expression of low molecular weight protein tyrosine phosphatase in gastric cancer and its association with clinical outcomes and oncogenic hallmarks

胃癌中低分子量蛋白酪氨酸磷酸酶的表达及其与临床结果和致癌特征的关系

期刊:Molecular Medicine

影响因子:6

doi:10.1186/s10020-025-01418-9.

Luochengling Xiang #,Ying Zhou #,Shanshan Li,Ron Smits,Jun Yu,Maikel P Peppelenbosch,Gwenny M Fuhler

Leveraging fragment-based drug discovery to advance 3D scaffolds into potent ligands: application to the histamine H(1) receptor

利用基于片段的药物发现方法将3D支架转化为高效配体：以组胺H(1)受体为例

期刊:RSC Medicinal Chemistry

影响因子:3.6

doi:10.1039/d5md01081k

Dekker, Tom; van Linden, Oscar P J; Lim, Herman D; Dekker, Mabel E; Vischer, Henry F; Leurs, Rob; van der Meer, Tiffany; Buzink, Maurice C M L; Hamilton, David J; Zarzycka, Barbara; Janssen, Elwin; Wijtmans, Maikel; de Esch, Iwan J P

Seasons and vertical dynamics influence community composition in a flooded and abandoned mica mine

季节和垂直动态变化影响着一座废弃云母矿中群落的组成。

期刊:FEMS Microbiology Ecology

影响因子:3.2

doi:10.1093/femsec/fiaf131

Lhoste, Elise; Jaclin, David; Ponsin, Violaine; Rosabal, Maikel; Sara Lazar, Cassandre

发表日期：2026

文献求助收藏

Comment on Catanzaro et al. Risk Factors for Recurrence of Primary Sclerosing Cholangitis after Liver Transplantation: Single-Center Data. J. Pers. Med. 2024, 14, 222

对 Catanzaro 等人发表的《肝移植后原发性硬化性胆管炎复发的危险因素：单中心数据》（J. Pers. Med. 2024, 14, 222）一文的评论

期刊:Journal of Personalized Medicine

影响因子:3

doi:10.3390/jpm16010054

Mammadov, Ruslan A; Roest, Henk P; Peppelenbosch, Maikel P; van der Laan, Luc J W

发表日期：2026

文献求助收藏

Acute and Chronic Toxicity of Sediments Containing Platinum and Palladium on Freshwater Benthic Organisms Chironomus riparius and Hyalella azteca

含铂钯沉积物对淡水底栖生物摇蚊（Chironomus riparius）和阿兹特克水母（Hyalella azteca）的急性和慢性毒性

期刊:Journal of Applied Toxicology

影响因子:2.8

doi:10.1002/jat.4933

Carle, Alice; Preizal, Ludivine; Amyot, Marc; Rosabal, Maikel

毒理研究

发表日期：2026

文献求助收藏

Second Virial Coefficients for N(2)···H(2) and NH···NH

N₂···H₂ 和 NH···NH 的第二维里系数

期刊:Journal of Physical Chemistry A

影响因子:2.8

doi:10.1021/acs.jpca.5c04624

Alves, Marcos D S; Ballester, Maikel Y

发表日期：2026

文献求助收藏

Risk of Poststroke Epilepsy Among Young Adults With Ischemic Stroke or Intracerebral Hemorrhage

缺血性卒中或脑出血青年患者发生卒中后癫痫的风险

期刊:Jama Neurology

影响因子:21.3

doi:10.1001/jamaneurol.2025.0465

Verburgt, Esmée; Fellah, Lina; Ekker, Merel S; Schellekens, Mijntje M I; Boot, Esther M; Immens, Maikel H M; van Alebeek, Mayte E; Brouwers, Paul J A M; Arntz, Renate M; van Dijk, Gert W; Gons, Rob A R; van Uden, Inge W M; den Heijer, Tom; van Tuijl, Julia H; de Laat, Karlijn F; van Norden, Anouk G W; Vermeer, Sarah E; van Zagten, Marian S G; van Oostenbrugge, Robert J; Wermer, Marieke J H; Nederkoorn, Paul J; Kerkhoff, Henk; Rooyer, Fergus A; van Rooij, Frank G; van den Wijngaard, Ido R; Tuladhar, Anil M; Verhoeven, Jamie I; Hilkens, Nina A; de Leeuw, Frank-Erik

The representation of omitted sounds in the mouse auditory cortex

小鼠听觉皮层中对省略声音的表征

Human liver-derived organoids recapitulate Oropouche virus infection and manifestation, enabling antiviral drug discovery

人肝源性类器官能够重现奥罗普切病毒的感染和临床表现，从而有助于抗病毒药物的研发。

Selective SIK2/SIK3 inhibition reprograms pro- and antiinflammatory pathways in myeloid cells, improving autoimmune disease outcomes

选择性抑制SIK2/SIK3可重编程髓系细胞中的促炎和抗炎通路，从而改善自身免疫性疾病的预后。

Expression of low molecular weight protein tyrosine phosphatase in gastric cancer and its association with clinical outcomes and oncogenic hallmarks

胃癌中低分子量蛋白酪氨酸磷酸酶的表达及其与临床结果和致癌特征的关系

Leveraging fragment-based drug discovery to advance 3D scaffolds into potent ligands: application to the histamine H(1) receptor

利用基于片段的药物发现方法将3D支架转化为高效配体：以组胺H(1)受体为例

Seasons and vertical dynamics influence community composition in a flooded and abandoned mica mine

季节和垂直动态变化影响着一座废弃云母矿中群落的组成。

Comment on Catanzaro et al. Risk Factors for Recurrence of Primary Sclerosing Cholangitis after Liver Transplantation: Single-Center Data. J. Pers. Med. 2024, 14, 222

对 Catanzaro 等人发表的《肝移植后原发性硬化性胆管炎复发的危险因素：单中心数据》（J. Pers. Med. 2024, 14, 222）一文的评论

Acute and Chronic Toxicity of Sediments Containing Platinum and Palladium on Freshwater Benthic Organisms Chironomus riparius and Hyalella azteca

含铂钯沉积物对淡水底栖生物摇蚊（Chironomus riparius）和阿兹特克水母（Hyalella azteca）的急性和慢性毒性

Second Virial Coefficients for N(2)···H(2) and NH···NH

N₂···H₂ 和 NH···NH 的第二维里系数

Risk of Poststroke Epilepsy Among Young Adults With Ischemic Stroke or Intracerebral Hemorrhage

缺血性卒中或脑出血青年患者发生卒中后癫痫的风险