日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inhibiting Disulfide Bonding in Truncated Tau297-391 Results in Enhanced Self-Assembly of Tau into Seed-Competent Assemblies

抑制截短的Tau297-391中的二硫键形成可增强Tau蛋白自组装成具有种子形成能力的复合物。

Oakley, Sebastian S; Marshall, Karen E; Meisl, Georg; Copsey, Alice; Maina, Mahmoud B; Milton, Robert; Vorley, Thomas; Storey, John M D; Harrington, Charles R; Wischik, Claude M; Xue, Wei-Feng; Serpell, Louise C

Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference

深入了解tau蛋白病的病理生理学、生物标志物和治疗方法:Tau2024全球会议论文集

Frost, Bess; Rowe, James B; Akinyemi, Rufus O; Abisambra, Jose F; Ashton, Nicholas J; Brendel, Matthias; Buée, Luc; Butler, David; Carrillo, Maria C; Chung, Peter; Clelland, Claire D; DeVos, Sarah L; Diaz, Kristophe; Edelmayer, Rebecca M; Elahi, Fanny M; Ellajosyula, Ratnavalli; Ewen, Colin; Fontana, Igor Camargo; Galas, Marie-Christine; Hansson, Oskar; Höglinger, Günter; Horie, Kanta; Ibanez, Agustín; Jacobs, Linde; Maina, Mahmoud B; Malpetti, Maura; McDade, Eric; McEwan, Will; Montoliu-Gaya, Laia; Mummery, Catherine J; Orr, Miranda E; Rohrer, Jonathan D; Rommel, Amy; Sastre, Carlos; Spires-Jones, Tara L; Tee, Boon Lead; Viney, Tim J; Walker, Jamie M; Wegmann, Susanne; Wildsmith, Kristin; Yadav, Ravi; Mahinrad, Simin; Sexton, Claire

Somatic and Stem Cell Bank to study the contribution of African ancestry to dementia: African iPSC Initiative.

建立体细胞和干细胞库,研究非洲血统对痴呆症的影响:非洲iPSC计划

Maina Mahmoud B, Isah Murtala B, Marsh Jacob A, Muhammad Zaid, Babazau Larema, Idris Abdulrahman Alkhamis, Aladyeva Ekaterina, Miller Nadia, Starr Emma, Miller Katherine J, Lee Scott, Minaya Miguel, Wray Selina, Harari Oscar, Goni Baba W, Serpell Louise C, Karch Celeste M

Mutant MAPT Induces rDNA Transcriptional Hyperactivation and Nucleolar Stress in Cellular Models

突变型MAPT在细胞模型中诱导rDNA转录过度激活和核仁应激

Muhammad, Zaid; Gu, Yan; Kwairanga, Suleiman H; Bailey, Laura J; Khan, Amna; Nasser, Mohammad; Aljarrah, Dana; Arber, Charles; Wray, Selina; Serpell, Louise C; Karch, Celeste M; Maina, Mahmoud B

In Silico Identification of a Potential TNF-Alpha Binder Using a Structural Similarity: A Potential Drug Repurposing Approach to the Management of Alzheimer's Disease

利用结构相似性进行计算机模拟鉴定潜在的TNF-α结合剂:一种治疗阿尔茨海默病的潜在药物再利用方法

Tettevi, Edward Jenner; Kuevi, Deryl Nii Okantey; Sumabe, Balagra Kasim; Simpong, David Larbi; Maina, Mahmoud B; Dongdem, Julius T; Osei-Atweneboana, Mike Y; Ocloo, Augustine

Dityrosine cross-linking and its potential roles in Alzheimer's disease

二酪氨酸交联及其在阿尔茨海默病中的潜在作用

Maina, Mahmoud B; Al-Hilaly, Youssra K; Serpell, Louise C

Shapeshifting tau: from intrinsically disordered to paired-helical filaments

变形的tau蛋白:从固有无序结构到成对螺旋丝状结构

Mengham, Kurtis; Al-Hilaly, Youssra; Oakley, Sebastian; Kasbi, Kamillia; Maina, Mahmoud B; Serpell, Louise C

Metal- and UV- Catalyzed Oxidation Results in Trapped Amyloid-β Intermediates Revealing that Self-Assembly Is Required for Aβ-Induced Cytotoxicity

金属和紫外线催化氧化导致淀粉样蛋白β中间体被捕获,表明自组装是Aβ诱导细胞毒性的必要条件。

Maina, Mahmoud B; Burra, Gunasekhar; Al-Hilaly, Youssra K; Mengham, Kurtis; Fennell, Kate; Serpell, Louise C

The Involvement of Aβ42 and Tau in Nucleolar and Protein Synthesis Machinery Dysfunction

Aβ42和Tau蛋白参与核仁和蛋白质合成机制功能障碍

Maina, Mahmoud B; Bailey, Laura J; Doherty, Aidan J; Serpell, Louise C