A pan-cancer single-cell analysis reveals the effect of PD-1 blockades on tumor angiogenesis by inhibiting the endothelial CXCL12-CXCR4 axis
泛癌单细胞分析揭示了PD-1阻断剂通过抑制内皮细胞CXCL12-CXCR4轴对肿瘤血管生成的影响。
期刊:Cancer Immunology Immunotherapy
影响因子:5.1
doi:10.1007/s00262-025-04188-9
Muhetarijiang, Mairedan; Zhu, Pengwei; Zhang, Han; Sun, Xiangjie; Wu, Yakui; Xu, Qianwen; Justin, Ryan; Li, Chenxi; Zhou, Dongchen; Zhang, Biqi; Liu, Jun; Hu, Xiaosheng; Chen, Ting
CXCL12
肿瘤
肿瘤免疫
CXCL1
CXCR4
血管生成
内皮细胞
细胞生物学
PD-1
单细胞
