日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Prognostic value of peri-operative circulating tumour DNA levels estimated by cell-free DNA methylation in patients with resectable colorectal liver metastases

通过游离DNA甲基化评估围手术期循环肿瘤DNA水平对可切除结直肠癌肝转移患者的预后价值

期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2026.106236
Makrodimitris, Stavros; Wullaert, Lissa; Hazelaar, Daan; Değer, Teoman; Boers, Ruben G; van de Wiel, Mark A; Jansen, Maurice Phm; Kraan, Jaco; Boers, Joachim B; van IJcken, Wilfred Fj; Beaufort, Corine M; de Weerd, Vanja; Sleijfer, Stefan; Gribnau, Joost; Vermaas, Maarten; Belt, Eric Jt; Gobardhan, Paul D; Verheul, Henk Mw; Grűnhagen, Dirk J; Martens, John Wm; Verhoef, Cornelis; Wilting, Saskia M
肿瘤
肠癌
表观遗传
肿瘤免疫
DNA甲基化
发表日期：2026
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Circulating tumour cells & circulating tumour DNA in patients with resectable colorectal liver metastases (MIRACLE): a prospective, observational biomarker study

可切除结直肠癌肝转移患者循环肿瘤细胞和循环肿瘤DNA（MIRACLE）：一项前瞻性观察性生物标志物研究

期刊:EClinicalMedicine
影响因子:10
doi:10.1016/j.eclinm.2025.103406
Wullaert, Lissa; Jansen, Maurice P H M; Kraan, Jaco; Meyer, Yannick M; Voigt, Kelly; Makrodimitris, Stavros; de Weerd, Vanja; Beaufort, Corine M; Van, Mai; Vermaas, Maarten; Belt, Eric J T; Gobardhan, Paul D; Sleijfer, Stefan; Verheul, Henk M W; Martens, John W M; Grünhagen, Dirk J; Wilting, Saskia M; Verhoef, Cornelis
肿瘤
肠癌
肿瘤免疫
细胞生物学
肿瘤细胞
发表日期：2025
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Improved circulating tumor DNA profiling by simultaneous extraction of DNA methylation and copy number information from methylated DNA sequencing data

通过同时从甲基化DNA测序数据中提取DNA甲基化和拷贝数信息，改进循环肿瘤DNA图谱分析。

期刊:npj Precision Oncology
影响因子:8
doi:10.1038/s41698-025-01237-5
Hazelaar, Daan M; Boers, Ruben G; Boers, Joachim B; de Weerd, Vanja; Helmijr, Jean; Phm Jansen, Maurice; Mw Verheul, Henk; Verhoef, Cornelis; Gribnau, Joost; Martens, John Wm; Makrodimitris, Stavros; Wilting, Saskia M
肿瘤
表观遗传
肿瘤免疫
DNA甲基化
发表日期：2025
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Methylated CfDNA may distinguish between high- and intermediate-risk uveal melanoma: a pilot study

甲基化CfDNA可能区分高危和中危葡萄膜黑色素瘤：一项初步研究

期刊:Cancer Cell International
影响因子:6
doi:10.1186/s12935-025-04093-2
Wu, Mike; de Bruyn, Daniël P; Boers, Ruben G; Beasley, Aaron B; Hazelaar, Daan M; Makrodimitris, Stavros; Boers, Joachim B; Vaarwater, Jolanda; de Keizer, Ronald O B; Verdijk, Robert M; Naus, Nicole C; Paridaens, Dion; Wilting, Saskia M; Gray, Elin S; van IJcken, Wilfred F J; Gribnau, Joost; de Klein, Annelies; Brosens, Erwin; Kiliç, Emine
黑色素瘤
表观遗传
发表日期：2025
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A comparative study of four cell-free DNA assays for detecting circulating tumor DNA in early breast cancer

四种无细胞DNA检测方法在早期乳腺癌循环肿瘤DNA检测中的比较研究

期刊:Breast Cancer Research
影响因子:5.6
doi:10.1186/s13058-025-02077-8
Mulder, Charlotta V; Jongbloed, Elisabeth M; Liefaard, Marte C; Makrodimitris, Stavros; Hazelaar, Daan M; Beaufort, Corine M; de Weerd, Vanja; Mulder, Lennart; van Deurzen, Carolien H M; Sonke, Gabe S; Jager, Agnes; Wilting, Saskia M; Martens, John W M; Jansen, Maurice P H M; Lips, Esther H
细胞生物学
肿瘤
肿瘤免疫
乳腺癌
发表日期：2025
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Epigenetic and Genomic Hallmarks of PARP-Inhibitor Resistance in Ovarian Cancer Patients

卵巢癌患者PARP抑制剂耐药性的表观遗传学和基因组学特征

期刊:Genes
影响因子:2.8
doi:10.3390/genes15060750
Senturk Kirmizitas, Tugce; van den Berg, Caroline; Boers, Ruben; Helmijr, Jean; Makrodimitris, Stavros; Dag, Hamit Harun; Kerkhofs, Marijn; Beaufort, Corine; Kraan, Jaco; van IJcken, Wilfred F J; Gribnau, Joost; Garkhail, Pakriti; Boer, Gatske Nieuwenhuyzen-de; Roes, Eva-Maria; van Beekhuizen, Heleen; Gunel, Tuba; Wilting, Saskia; Martens, John; Jansen, Maurice; Boere, Ingrid
肿瘤
表观遗传
肿瘤免疫
卵巢癌
PARP
发表日期：2024
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Cell type deconvolution of methylated cell-free DNA at the resolution of individual reads

以单个读取分辨率对甲基化游离DNA进行细胞类型反卷积

期刊:NAR Genomics and Bioinformatics
影响因子:2.8
doi:10.1093/nargab/lqad048
Keukeleire, Pia; Makrodimitris, Stavros; Reinders, Marcel
细胞生物学
表观遗传
发表日期：2023
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Benchmarking variational AutoEncoders on cancer transcriptomics data

在癌症转录组数据上对变分自编码器进行基准测试

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0292126
Eltager, Mostafa; Abdelaal, Tamim; Charrout, Mohammed; Mahfouz, Ahmed; Reinders, Marcel J T; Makrodimitris, Stavros
肿瘤
肿瘤免疫
发表日期：2023
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The Power of Universal Contextualized Protein Embeddings in Cross-species Protein Function Prediction

通用上下文蛋白质嵌入在跨物种蛋白质功能预测中的强大作用

期刊:Evolutionary Bioinformatics
影响因子:1.5
doi:10.1177/11769343211062608
van den Bent, Irene; Makrodimitris, Stavros; Reinders, Marcel
发表日期：2021
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Unsupervised protein embeddings outperform hand-crafted sequence and structure features at predicting molecular function

无监督蛋白质嵌入在预测分子功能方面优于手工设计的序列和结构特征。

期刊:
影响因子:
doi:10.1093/bioinformatics/btaa701
Villegas-Morcillo, Amelia; Makrodimitris, Stavros; van Ham, Roeland C H J; Gomez, Angel M; Sanchez, Victoria; Reinders, Marcel J T
发表日期：2021
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