日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A hotspot phosphorylation site on SHP2 drives oncoprotein activation and drug resistance

SHP2上的热点磷酸化位点驱动癌蛋白活化和耐药性。

Karunaraj, Prashath; Scheele, Remkes; Wells, Malcolm L; Rathod, Ruchita; Gokulu, Ipek S; Abrahamson, Sophia R; Taylor, Lila; Chowdhury, Lamia; Kazmi, Abiha; Song, Weixiao; Hornbeck, Peter V; Li, Jing; Glasgow, Anum; Vasan, Neil

Bidirectional allosteric ligand regulation in a central glycolytic enzyme.

糖酵解中心酶的双向变构配体调节。

Sundberg Belen, Lu Chenlin, Wells Malcolm L, Weber Kyle C, Gong Zhen, Glasgow Anum

Prefusion structure, evasion and neutralization of HSV-1 glycoprotein B

融合前结构、HSV-1糖蛋白B的逃避和中和

Ryan S Roark,Andrew J Schaub,Wei Shi,Maple Wang,Fabiana A Bahna,Jordan E Becker,Andrea Biju,Sue Chong,Haijuan Du,Yicheng Guo,Hsiang Hong,Phinikoula S Katsamba,Seetha M Mannepalli,Adam S Olia,Li Ou,Sarah K Rubin,Yosef Sabo,Mehin Suleiman,Malcolm L Wells,Baoshan Zhang,Cheng Cheng,Anum Glasgow,David D Ho,Yaoxing Huang,Theodore C Pierson,Reda Rawi,Tongqing Zhou,Lawrence Shapiro,Peter D Kwong

Free thyroxine measured by chemiluminescence and equilibrium dialysis is frequently below the reference interval in known euthyroid dogs with nonthyroidal illness syndrome

在已知甲状腺功能正常的犬中,采用化学发光法和平衡透析法测定的游离甲状腺素水平通常低于非甲状腺疾病综合征的参考区间。

Bolton, Timothy A; Marino, Christina L; Derré, Maxime G; Moore, George E; Piccione, Julie; Delovio, Malcolm L

Conserved energetic changes drive function in an ancient protein fold

保守的能量变化驱动着古老蛋白质折叠的功能

Wells, Malcolm L; Lu, Chenlin; Sultanov, Daniel; Weber, Kyle C; Gong, Zhen; Glasgow, Anum

Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia

线粒体对急性髓系白血病中 GPX4 抑制介导的铁死亡的调节

Hiroki Akiyama, Ran Zhao, Lauren B Ostermann, Ziyi Li, Matthew Tcheng, Samar J Yazdani, Arman Moayed, Malcolm L Pryor 2nd, Sandeep Slngh, Natalia Baran, Edward Ayoub, Yuki Nishida, Po Yee Mak, Vivian R Ruvolo, Bing Z Carter, Aaron D Schimmer, Michael Andreeff, Jo Ishizawa

Transthyretin cardiac amyloid: Broad heart failure phenotypic spectrum and implications for diagnosis

转甲状腺素蛋白心脏淀粉样变性:广泛的心力衰竭表型谱及其对诊断的意义

Alonso, Mileydis; Neicheril, Radhika K; Manla, Yosef; McDonald, Malcolm L; Sanchez, Alejandro; Lafave, Gabrielle; Seijo De Armas, Yelenis; Camargo, Antonio Lewis; Uppal, Dipan; Wolinsky, David; Thakkar-Rivera, Nina; Velez, Mauricio; Baran, David A; Estep, Jerry D; Snipelisky, David

Predictors of developing renal dysfunction following diagnosis of transthyretin cardiac amyloidosis

转甲状腺素蛋白心脏淀粉样变性诊断后发生肾功能障碍的预测因素

McDonald, Malcolm L; Manla, Yosef; Sonnino, Alice; Alonso, Mileydis; Neicheril, Radhika K; Sanchez, Alejandro; Lafave, Gabrielle; Armas, Yelenis Seijo De; Camargo, Antonio Lewis; Uppal, Dipan; Handa, Armaan; Wolinsky, David; Rivera, Nina Thakkar; Velez, Mauricio; Baran, David A; Estep, Jerry D; Snipelisky, David

Machine learning enabled design features of antimicrobial peptides selectively targeting peri-implant disease progression

机器学习技术能够设计选择性靶向种植体周围疾病进展的抗菌肽特征。

Boone, Kyle; Tjokro, Natalia; Chu, Kalea N; Chen, Casey; Snead, Malcolm L; Tamerler, Candan

Author Correction: Ligand-specific changes in conformational flexibility mediate long-range allostery in the lac repressor

作者更正:配体特异性的构象柔性变化介导乳糖阻遏蛋白的长程变构作用

Glasgow, Anum; Hobbs, Helen T; Perry, Zion R; Wells, Malcolm L; Marqusee, Susan; Kortemme, Tanja