日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Covalent Labeling of Matrix Metalloproteases with Affinity-Based Probes Containing Tuned Reactive N-Acyl-N-Alkyl Sulfonamide Cleavable Linkers

利用含有可调控反应性N-酰基-N-烷基磺酰胺可裂解连接子的亲和探针,对基质金属蛋白酶进行共价标记

Devel, Laurent; Malgorn, Carole; Tohon, Regis-William; Launay, Marie; Patiniotis, Konstantinos; Sejalon-Cipolla, Mylene; Beau, Fabrice; Thai, Robert; Bruyat, Pierrick; Bonino, Annabelle; Bregant, Sarah; Subra, Gilles; Cantel, Sonia; Georgiadis, Dimitris

Monitoring In Vivo Performances of Protein-Drug Conjugates Using Site-Selective Dual Radiolabeling and Ex Vivo Digital Imaging

利用位点选择性双放射性标记和离体数字成像技术监测蛋白质-药物偶联物的体内性能

Cahuzac, Héloïse; Sallustrau, Antoine; Malgorn, Carole; Beau, Fabrice; Barbe, Peggy; Babin, Victor; Dubois, Steven; Palazzolo, Alberto; Thai, Robert; Correia, Isabelle; Lee, Ki Baek; Garcia-Argote, Sébastien; Lequin, Olivier; Keck, Mathilde; Nozach, Hervé; Feuillastre, Sophie; Ge, Xin; Pieters, Gregory; Audisio, Davide; Devel, Laurent

Age-associated evolution of plasmatic amyloid in mouse lemur primates: relationship with intracellular amyloid deposition

小鼠狐猴灵长类动物血浆淀粉样蛋白的年龄相关演变:与细胞内淀粉样蛋白沉积的关系

Roy, Maggie; Cardoso, Cécile; Dorieux, Olène; Malgorn, Carole; Epelbaum, Stéphane; Petit, Fanny; Kraska, Audrey; Brouillet, Emmanuel; Delatour, Benoît; Perret, Martine; Aujard, Fabienne; Dhenain, Marc

Impaired brain energy metabolism in the BACHD mouse model of Huntington's disease: critical role of astrocyte-neuron interactions

亨廷顿氏病 BACHD 小鼠模型中的大脑能量代谢受损:星形胶质细胞-神经元相互作用的关键作用

Lydie Boussicault, Anne-Sophie Hérard, Noel Calingasan, Fanny Petit, Carole Malgorn, Nicolas Merienne, Caroline Jan, Marie-Claude Gaillard, Rodrigo Lerchundi, Luis F Barros, Carole Escartin, Thierry Delzescaux, Jean Mariani, Philippe Hantraye, M Flint Beal, Emmanuel Brouillet, Céline Véga, Gilles Bo

A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin

线粒体复合物II缺陷在表达突变亨廷顿蛋白N端片段的亨廷顿病遗传模型中的作用

Damiano, Maria; Diguet, Elsa; Malgorn, Carole; D'Aurelio, Marilena; Galvan, Laurie; Petit, Fanny; Benhaim, Lucile; Guillermier, Martine; Houitte, Diane; Dufour, Noelle; Hantraye, Philippe; Canals, Josep M; Alberch, Jordi; Delzescaux, Thierry; Déglon, Nicole; Beal, M Flint; Brouillet, Emmanuel

IRC-082451, a novel multitargeting molecule, reduces L-DOPA-induced dyskinesias in MPTP Parkinsonian primates

IRC-082451 是一种新型多靶点分子,可减轻 MPTP 帕金森病灵长类动物中左旋多巴诱导的运动障碍。

Aron Badin, Romina; Spinnewyn, Brigitte; Gaillard, Marie-Claude; Jan, Caroline; Malgorn, Carole; Van Camp, Nadja; Dollé, Frédéric; Guillermier, Martine; Boulet, Sabrina; Bertrand, Anne; Savasta, Marc; Auguet, Michel; Brouillet, Emmanuel; Chabrier, Pierre-Etienne; Hantraye, Philippe

Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II

多巴胺通过调节线粒体复合物II来决定纹状体神经元对突变亨廷顿蛋白N端片段的易感性。

Benchoua, Alexandra; Trioulier, Yaël; Diguet, Elsa; Malgorn, Carole; Gaillard, Marie-Claude; Dufour, Noelle; Elalouf, Jean-Marc; Krajewski, Stan; Hantraye, Philippe; Déglon, Nicole; Brouillet, Emmanuel