日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Palbociclib and dsRNA sensor co-operate to enhance anti-cancer effects through ER stress and modulation of immune evasion

Palbociclib 和 dsRNA 传感器协同作用，通过内质网应激和调节免疫逃逸来增强抗癌作用。

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-025-60133-5
Victoria Roulstone # ，Joan Kyula-Currie # ，James Wright ，Emmanuel C Patin ，Isaac Dean ，Lu Yu ，Aida Barreiro-Alonso ，Miriam Melake ，Jyoti Choudhary ，Richard Elliott ，Christopher J Lord ，David Mansfield ，Nik Matthews ，Ritika Chauhan ，Victoria Jennings ，Charleen Chan Wah Hak ，Holly Baldock ，Francesca Butera ，Elizabeth Appleton ，Pablo Nenclares ，Malin Pedersen ，Shane Foo ，Amarin Wongariyapak ，Antonio Rullan ，Tencho Tenev ，Pascal Meier ，Richard Vile ，Hardev Pandha ，Alan Melcher ，Martin McLaughlin ，Kevin J Harrington
免疫/内分泌
肿瘤
BOC
ALB
肿瘤免疫
发表日期：2025
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ARID1A stabilizes non-homologous end joining factors at DNA breaks induced by the G4 ligand pyridostatin

ARID1A 可稳定由 G4 配体吡啶斯他汀诱导的 DNA 断裂处的非同源末端连接因子。

期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2025.116277.
Susana Simões-Sousa ,Noa Amin ,Karen A Lane ,Alison Harrod ,Malin Pedersen ,Mercedes Pardo ,Christine Rasetti-Escargueil ,Zuzanna Kozik ,Katheryn A G Begg ,Alison Ribeiro ,Susana Banerjee ,Manuel Stucki ,Kevin J Harrington ,Jyoti S Choudhary ,Jessica A Downs
T细胞
ID1
ARID1A
发表日期：2025
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Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent adjuvant immunotherapy

通过放射治疗和 ATR 抑制相结合来塑造肿瘤微环境，以实现治愈性辅助免疫治疗

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-024-51236-6
Emmanuel C Patin, Pablo Nenclares, Charleen Chan Wah Hak, Magnus T Dillon, Anton Patrikeev, Martin McLaughlin, Lorna Grove, Shane Foo, Heba Soliman, Joao P Barata, Joanna Marsden, Holly Baldock, Jim Gkantalis, Victoria Roulstone, Joan Kyula, Amy Burley, Lisa Hubbard, Malin Pedersen, Simon A Smith, E
肿瘤
发表日期：2024
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Combination of oncolytic Maraba virus with immune checkpoint blockade overcomes therapy resistance in an immunologically cold model of advanced melanoma with dysfunctional T-cell receptor signalling

溶瘤马拉巴病毒与免疫检查点阻断相结合，克服了 T 细胞受体信号传导功能障碍的晚期黑色素瘤免疫冷模型中的治疗耐药性

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.3
doi:10.1136/jitc-2024-009443
Edward Armstrong, Matthew K L Chiu, Shane Foo, Lizzie Appleton, Pablo Nenclares, Anton Patrikeev, Nitya Mohan, Martin Mclaughlin, Galabina Bozhanova, Julia Hoebart, Victoria Roulstone, Emmanuel Patin, Malin Pedersen, Joan Kyula, Masahiro Ono, Fiona Errington-Mais, John Bell, Kevin J Harrington, Alan
信号转导
微生物学
肿瘤
黑色素瘤
T细胞
Checkpoint
T Cell Receptor
发表日期：2024
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Characterization of proteome-size scaling by integrative omics reveals mechanisms of proliferation control in cancer

通过整合组学表征蛋白质组尺寸缩放揭示癌症增殖控制机制

期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.add0636
Ian Jones, Lucas Dent, Tomoaki Higo, Theodoros Roumeliotis, Maria Arias Garcia, Hansa Shree, Jyoti Choudhary, Malin Pedersen, Chris Bakal
肿瘤
HTRF
发表日期：2023
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Mosaic Loss of Chromosome Y Is Associated With Functional Outcome After Ischemic Stroke

Y染色体嵌合体缺失与缺血性卒中后的功能预后相关

期刊:Stroke
影响因子:8.9
doi:10.1161/STROKEAHA.123.043551
Dorvall, Malin; Pedersen, Annie; Dumanski, Jan P; Söderholm, Martin; Lindgren, Arne G; Stanne, Tara M; Jern, Christina
发表日期：2023
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Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma

对抗 MAPK 靶向治疗的获得性耐药性赋予了黑色素瘤免疫逃避肿瘤微环境和对免疫治疗的交叉耐药性

期刊:Nature Cancer
影响因子:23.5
doi:10.1038/s43018-021-00221-9
Lisa Haas, Anais Elewaut, Camille L Gerard, Christian Umkehrer, Lukas Leiendecker, Malin Pedersen, Izabela Krecioch, David Hoffmann, Maria Novatchkova, Mario Kuttke, Tobias Neumann, Ines Pires da Silva, Harriet Witthock, Michel A Cuendet, Sebastian Carotta, Kevin J Harrington, Johannes Zuber, Richar
信号转导
肿瘤
黑色素瘤
MAPK/ERK
发表日期：2021
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Genetic Predisposition to Mosaic Chromosomal Loss Is Associated With Functional Outcome After Ischemic Stroke

遗传易感性导致嵌合型染色体缺失与缺血性卒中后的功能预后相关

期刊:Neurology-Genetics
影响因子:3.7
doi:10.1212/NXG.0000000000000634
Johansson, Malin; Pedersen, Annie; Cole, John W; Lagging, Cecilia; Lindgren, Arne; Maguire, Jane M; Rost, Natalia S; Söderholm, Martin; Worrall, Bradford B; Stanne, Tara M; Jern, Christina
发表日期：2021
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Combining BRAF inhibition with oncolytic herpes simplex virus enhances the immune-mediated antitumor therapy of BRAF-mutant thyroid cancer

BRAF 抑制与溶瘤单纯疱疹病毒相结合可增强 BRAF 突变型甲状腺癌的免疫介导抗肿瘤治疗

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.3
doi:10.1136/jitc-2020-000698
Eva Crespo-Rodriguez, Katharina Bergerhoff, Galabina Bozhanova, Shane Foo, Emmanuel C Patin, Harriet Whittock, Richard Buus, Syed Haider, Gareth Muirhead, Khin Thway, Kate Newbold, Robert S Coffin, Richard G Vile, Dae Kim, Martin McLaughlin, Alan A Melcher, Kevin J Harrington, Malin Pedersen
信号转导
免疫
微生物学
疱疹
发表日期：2020
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The PERK Inhibitor GSK2606414 Enhances Reovirus Infection in Head and Neck Squamous Cell Carcinoma via an ATF4-Dependent Mechanism

PERK 抑制剂 GSK2606414 通过 ATF4 依赖性机制增强头颈部鳞状细胞癌中的呼肠孤病毒感染

期刊:Molecular Therapy-Oncolytics
影响因子:5.3
doi:10.1016/j.omto.2020.01.001
Martin McLaughlin, Malin Pedersen, Victoria Roulstone, Katharina F Bergerhoff, Henry G Smith, Harriet Whittock, Joan N Kyula, Magnus T Dillon, Hardev S Pandha, Richard Vile, Alan A Melcher, Kevin J Harrington
信号转导
微生物学
肿瘤
头颈癌
其它细胞
IHC
MAPK/ERK
发表日期：2020
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