Dengue virus NS1 leads to downregulation of HNF4 alpha in liver cells resulting in a decrease in coagulation factors I, V, X, and XIII, contributing to coagulopathy.
登革病毒 NS1 导致肝细胞中 HNF4 α 下调，从而导致凝血因子 I、V、X 和 XIII 减少，进而导致凝血功能障碍
期刊:Journal of Virology
影响因子:3.8
doi:10.1128/jvi.01418-24
Das Sandeepan, Mallik Md Hasan, Chattopadyay Partha, Mallick Susenjit, Karmakar Dibyajyoti, Ghora Subhadip, Begum Feroza, Chatterjee Bilash, Thagriki Dluya Samuel, Srivastava Amit Kumar, Ray Upasana
