An increased copy number of glycine decarboxylase (GLDC) associated with psychosis reduces extracellular glycine and impairs NMDA receptor function
精神病患者体内甘氨酸脱羧酶 (GLDC) 拷贝数增加，导致细胞外甘氨酸水平降低，并损害 NMDA 受体功能。
期刊:Molecular Psychiatry
影响因子:10.1
doi:10.1038/s41380-024-02711-5
Kambali, Maltesh; Li, Yan; Unichenko, Petr; Feria Pliego, Jessica A; Yadav, Rachita; Liu, Jing; McGuinness, Patrick; Cobb, Johanna G; Wang, Muxiao; Nagarajan, Rajasekar; Lyu, Jinrui; Vongsouthi, Vanessa; Jackson, Colin J; Engin, Elif; Coyle, Joseph T; Shin, Jaeweon; Hodgson, Nathaniel W; Hensch, Takao K; Talkowski, Michael E; Homanics, Gregg E; Bolshakov, Vadim Y; Henneberger, Christian; Rudolph, Uwe
