日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multiomic characterization of small cell lung cancer: Real-world insights into therapeutic opportunities

小细胞肺癌的多组学表征:对治疗机会的真实世界见解

Puri, Sonam; Elliott, Andrew; Naqash, Abdul Rafeh; Shukair, Hassan Abu; Kerrigan, Kathleen C; Patel, Shiven; Seeber, Andreas; Kocher, Florian; Uprety, Dipesh; Mamdani, Hirva; Kulkarni, Amit A; Lopes, Gilberto; Halmos, Balazs; Borghaei, Hossein; Akerley, Wallace; Sica, Gabriel L; Liu, Stephen V; Oliver, Trudy G; Owonikoko, Taofeek K

Complement factor H targeting antibody GT103 in refractory non-small cell lung cancer: a phase 1b dose escalation trial.

针对补体因子 H 的抗体 GT103 在难治性非小细胞肺癌中的应用:一项 1b 期剂量递增试验

Clarke Jeffrey M, Simon George R, Mamdani Hirva, Gu Lin, Herndon James E 2nd, Stinchcombe Thomas E, Ready Neal, Crawford Jeffrey, Sonpavde Guru, Balevic Stephen, Nixon Andrew B, Campa Michael, Gottlin Elizabeth B, Li Huihua, Saxena Ruchi, He You Wen, Antonia Scott, Patz Edward F Jr

Randomized phase II study of consolidation immunotherapy with nivolumab and ipilimumab or nivolumab alone following concurrent chemoradiotherapy for unresectable stage IIIA/IIIB non-small-cell lung cancer (NSCLC): Big Ten Cancer Research Consortium LUN16-081

一项随机 II 期研究,旨在评估在不可切除的 IIIA/IIIB 期非小细胞肺癌 (NSCLC) 患者接受同步放化疗后,采用纳武利尤单抗联合伊匹木单抗或单用纳武利尤单抗进行巩固免疫治疗的疗效:十大癌症研究联盟 LUN16-081

Durm, Greg; Mamdani, Hirva; Althouse, Sandra; Perkins, Susan; Jabbour, Salma K; Ganti, Apar Kishor; Jalal, Shadia; Chesney, Jason; Naidoo, Jarushka; Hrinczenko, Borys; Fidler, Mary Jo; Leal, Ticiana A; Feldman, Lawrence; Fujioka, Naomi; Hanna, Nasser H

Molecular and immune landscape of tumours in geriatric patients with non-small cell lung cancer, melanoma and renal cell carcinoma

老年非小细胞肺癌、黑色素瘤和肾细胞癌患者肿瘤的分子和免疫图谱

Choucair, Khalil; Elliott, Andrew; Oberley, Matthew James; Walker, Phillip; Salama, April K; Saeed, Azhar; Mamdani, Hirva; Uprety, Dipesh; El-Deiry, Wafik S; Beltran, Himisha; Liu, Stephen V; Kim, Chul; Naqash, Abdul Rafeh; Lou, Emil; Chen, Lujia; Saeed, Anwaar

Racial and socioeconomic disparities in survival among patients with metastatic non-small cell lung cancer

转移性非小细胞肺癌患者的生存率存在种族和社会经济差异

Uprety, Dipesh; Seaton, Randell; Hadid, Tarik; Mamdani, Hirva; Sukari, Ammar; Ruterbusch, Julie J; Schwartz, Ann G

Influence of TP53 Comutation on the Tumor Immune Microenvironment and Clinical Outcomes With Immune Checkpoint Inhibitors in STK11-Mutant Non-Small-Cell Lung Cancer

TP53共突变对STK11突变型非小细胞肺癌肿瘤免疫微环境及免疫检查点抑制剂临床疗效的影响

Naqash, Abdul Rafeh; Floudas, Charalampos S; Aber, Etan; Maoz, Asaf; Nassar, Amin H; Adib, Elio; Choucair, Khalil; Xiu, Joanne; Baca, Yasmine; Ricciuti, Biagio; Alessi, Joao V; Awad, Mark M; Kim, Chul; Judd, Julia; Raez, Luis E; Lopes, Gilberto; Nieva, Jorge J; Borghaei, Hossein; Takebe, Naoko; Ma, Patrick C; Halmos, Balazs; Kwiatkowski, David J; Liu, Stephen V; Mamdani, Hirva

Evaluation of the Effect of Lorlatinib on CYP2B6, CYP2C9, UGT, and P-Glycoprotein Substrates in Patients with Advanced Non-Small Cell Lung Cancer

评估洛拉替尼对晚期非小细胞肺癌患者CYP2B6、CYP2C9、UGT和P-糖蛋白底物的影响

Chen, Joseph; Bearz, Alessandra; Kim, Dong-Wan; Mamdani, Hirva; Bauman, Jessica; Chiari, Rita; Ou, Sai-Hong Ignatius; Solomon, Benjamin J; Soo, Ross A; Felip, Enriqueta; Shaw, Alice T; Thurm, Holger; Clancy, Jill S; Lee, Kimberly; O'Gorman, Melissa; Tanski, Cherie; Pithavala, Yazdi K

Evaluation of the Immune Response within the Tumor Microenvironment in African American and Non-Hispanic White Patients with Non-Small Cell Lung Cancer

对非小细胞肺癌患者(包括非西班牙裔白人和非西班牙裔美国人)肿瘤微环境中的免疫反应进行评估

Trendowski, Matthew R; Watza, Donovan; Lusk, Christine M; Lonardo, Fulvio; Ratliff, Valerie; Wenzlaff, Angela S; Mamdani, Hirva; Neslund-Dudas, Christine; Boerner, Julie L; Schwartz, Ann G; Gibson, Heather M

A phase II study evaluating safety and efficacy of niraparib in patients with previously treated homologous recombination defective metastatic esophageal/gastroesophageal junction/proximal gastric adenocarcinoma

一项评估尼拉帕尼治疗既往接受过治疗的同源重组缺陷型转移性食管/胃食管交界处/近端胃腺癌患者的安全性和有效性的II期研究

Khalid, Ahmed Bilal; Fountzilas, Christos; Burney, Heather N; Mamdani, Hirva; Schneider, Bryan P; Fausel, Christopher; Perkins, Susan M; Jalal, Shadia

Health Disparities among Patients with Cancer Who Received Molecular Testing for Biomarker-Directed Therapy

接受生物标志物定向治疗的癌症患者分子检测中存在的健康差异

Heath, Elisabeth; Dyson, Gregory; Ribeiro, Jennifer R; Xiu, Joanne; Poorman, Kelsey; Mamdani, Hirva; Al-Hallak, Mohammed N; Shields, Anthony F; Elayoubi, Jailan A; Winer, Ira S; Cackowski, Frank C; Puckrein, Gary A; Lopes, Gilberto de Lima; Jones, Nathaniel; Hauke, Ralph J; Kareff, Samuel A; Radovich, Milan; Sledge, George W; Spetzler, David B; Vidal, Gregory A; Marshall, John L