SESOTHO trial ("Switch Either near Suppression Or THOusand") - switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with viremia below 1000 copies/mL: protocol of a multicenter, parallel-group, open-label, randomized clinical trial in Lesotho, Southern Africa
SESOTHO试验(“病毒载量接近抑制或低于1000拷贝/毫升时切换治疗”)——针对一线抗逆转录病毒疗法(ART)治疗后病毒载量低于1000拷贝/毫升且病毒未得到抑制的患者,切换至二线治疗与世界卫生组织(WHO)指导的标准治疗方案的比较:一项在南部非洲莱索托开展的多中心、平行组、开放标签、随机临床试验方案。
期刊:BMC Infectious Diseases
影响因子:3
doi:10.1186/s12879-018-2979-y
Amstutz, Alain; Nsakala, Bienvenu Lengo; Vanobberghen, Fiona; Muhairwe, Josephine; Glass, Tracy Renée; Achieng, Beatrice; Sepeka, Mamorena; Tlali, Katleho; Sao, Lebohang; Thin, Kyaw; Klimkait, Thomas; Battegay, Manuel; Labhardt, Niklaus Daniel