日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cutting Edge: Hypoxia Sensing by the Histone Demethylase UTX (KDM6A) Limits Colitogenic CD4+ T Cells in Mucosal Inflammation

前沿研究:组蛋白去甲基化酶UTX(KDM6A)介导的缺氧感知限制了黏膜炎症中的致结肠炎CD4+ T细胞

Cheng, Mandy I; Hong, Lee; Bustillos, Christian; Chen, Bryan; Chin, Scott; Luthers, Christopher R; Vo, Au; Sheikh, Shehzad Z; Su, Maureen A

The X-linked epigenetic regulator UTX controls NK cell-intrinsic sex differences

连锁表观遗传调控因子 UTX 控制 NK 细胞内在性别差异

Mandy I Cheng, Joey H Li, Luke Riggan, Bryan Chen, Rana Yakhshi Tafti, Scott Chin, Feiyang Ma, Matteo Pellegrini, Haley Hrncir, Arthur P Arnold, Timothy E O'Sullivan, Maureen A Su

Hypoxia-sensing by the Histone Demethylase UTX ( KDM6A ) Controls Colitogenic CD4 (+) T cell Fate and Mucosal Inflammation

组蛋白去甲基化酶UTX(KDM6A)对缺氧的感知控制着致结肠炎CD4(+)T细胞的命运和黏膜炎症

Cheng, Mandy I; Hong, Lee; Chen, Bryan; Chin, Scott; Luthers, Christopher R; Bustillos, Christian; Sheikh, Shehzad Z; Su, Maureen A

Inhibition of IL-17A Protects against Thyroid Immune-Related Adverse Events while Preserving Checkpoint Inhibitor Antitumor Efficacy

抑制 IL-17A 可预防甲状腺免疫相关不良事件,同时保持检查点抑制剂的抗肿瘤功效

Melissa G Lechner, Mandy I Cheng, Anushi Y Patel, Aline T Hoang, Natalie Yakobian, Michael Astourian, Marissa S Pioso, Eduardo D Rodriguez, Ethan C McCarthy, Willy Hugo, Trevor E Angell, Alexandra Drakaki, Antoni Ribas, Maureen A Su

Pathogenic TNF-α drives peripheral nerve inflammation in an Aire-deficient model of autoimmunity

致病性 TNF-α 在 Aire 缺陷型自身免疫模型中引发周围神经炎症

Yan Wang, Lily Guo, Xihui Yin, Ethan C McCarthy, Mandy I Cheng, Aline T Hoang, Ho-Chung Chen, Anushi Y Patel, Denise Allard Trout, Erin Xu, Natalie Yakobian, Willy Hugo, James F Howard Jr, Katherine M Sheu, Alexander Hoffmann, Melissa G Lechner, Maureen A Su1

Deciphering immune mechanisms in chronic inflammatory demyelinating polyneuropathies

解读慢性炎症性脱髓鞘性多发性神经病中的免疫机制

Wolbert, Jolien; Cheng, Mandy I; Meyer zu Horste, Gerd; Su, Maureen A

TLR2 and endosomal TLR-mediated secretion of IL-10 and immune suppression in response to phagosome-confined Listeria monocytogenes

TLR2 和内体 TLR 介导的 IL-10 分泌和对吞噬体限制的单核细胞增生李斯特菌的免疫抑制

Brittney N Nguyen, Alfredo Chávez-Arroyo, Mandy I Cheng, Maria Krasilnikov, Alexander Louie, Daniel A Portnoy

Listeria monocytogenes triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy

单核细胞增生李斯特菌在吞噬作用后会触发非经典自噬,但会避免随后的生长限制性异噬作用。

Mitchell, Gabriel; Cheng, Mandy I; Chen, Chen; Nguyen, Brittney N; Whiteley, Aaron T; Kianian, Sara; Cox, Jeffery S; Green, Douglas R; McDonald, Kent L; Portnoy, Daniel A

Actin-based motility allows Listeria monocytogenes to avoid autophagy in the macrophage cytosol

基于肌动蛋白的运动能力使单核细胞增生李斯特菌能够避免在巨噬细胞胞质中自噬

Mandy I Cheng, Chen Chen, Patrik Engström, Daniel A Portnoy, Gabriel Mitchell

Neisseria gonorrhoeae with high-level resistance to azithromycin: case report of the first isolate identified in the United States

对阿奇霉素具有高度耐药性的淋病奈瑟菌:美国首例分离株病例报告

Katz, Alan R; Komeya, Alan Y; Soge, Olusegun O; Kiaha, Mandy I; Lee, Maria Veneranda C; Wasserman, Glenn M; Maningas, Eloisa V; Whelen, A Christian; Kirkcaldy, Robert D; Shapiro, Steven J; Bolan, Gail A; Holmes, King K