日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CTLA-4 Checkpoint Inhibition Improves Sepsis Survival in Alcohol-Exposed Mice

CTLA-4 检查点抑制可改善酒精暴露小鼠的脓毒症生存率

Cameron W Paterson, Katherine T Fay, Ching-Wen Chen, Nathan J Klingensmith, Melissa B Gutierrez, Zhe Liang, Craig M Coopersmith, Mandy L Ford

Claudin-2 upregulation enhances intestinal permeability, immune activation, dysbiosis, and mortality in sepsis

Claudin-2 上调可增强脓毒症患者的肠道通透性、免疫激活、菌群失调和死亡率

Takehiko Oami #, Shabnam Abtahi #, Takashi Shimazui, Ching-Wen Chen, Yan Y Sweat, Zhe Liang, Eileen M Burd, Alton B Farris, Joe T Roland, Sachiko Tsukita, Mandy L Ford, Jerrold R Turner, Craig M Coopersmith

FcγRIIB expressed on CD8+ T cells limits responsiveness to PD-1 checkpoint inhibition in cancer

CD8+ T 细胞上表达的 FcγRIIB 限制了癌症对 PD-1 检查点抑制的反应性

Kelsey B Bennion, Marvi Tariq, Megan M Wyatt, Charlotte Duneton, Kirsten M Baecher, Chrystal M Paulos, Ragini R Kudchadkar, Michael C Lowe, Mandy L Ford

Mitochondrial metabolic flexibility is critical for CD8+ T cell antitumor immunity

线粒体代谢灵活性对 CD8+ T 细胞抗肿瘤免疫至关重要

Chao Chen, Hong Zheng, Edwin M Horwitz, Satomi Ando, Koichi Araki, Peng Zhao, Zhiguo Li, Mandy L Ford, Rafi Ahmed, Cheng-Kui Qu

CHRONIC ETHANOL USE WORSENS GUT PERMEABILITY AND ALTERS TIGHT JUNCTION EXPRESSION IN A MURINE SEPSIS MODEL

在小鼠脓毒症模型中,长期饮用乙醇会恶化肠道通透性并改变紧密连接表达

Takehiko Oami, Tetsuya Yumoto, Takashi Shimazui, Sofia Sarmiento, Nathan J Klingensmith, Ching-Wen Chen, Shunsuke Otani, Zhe Liang, Eileen M Burd, Zaid K Mahdi, Mandy L Ford, Craig M Coopersmith

MYOSIN LIGHT CHAIN KINASE DELETION WORSENS LUNG PERMEABILITY AND INCREASES MORTALITY IN PNEUMONIA-INDUCED SEPSIS

肌球蛋白轻链激酶缺失使肺通透性恶化并增加肺炎诱发脓毒症的死亡率

Deena B Chihade, Prestina Smith, David A Swift, Shunsuke Otani, Wenxiao Zhang, Ching-Wen Chen, Lauren A Jeffers, Zhe Liang, Takashi Shimazui, Eileen M Burd, Alton B Farris, Bashar S Staitieh, David M Guidot, Mandy L Ford, Michael Koval, Craig M Coopersmith

Junctional adhesion molecule-A deletion increases phagocytosis and improves survival in a murine model of sepsis

连接粘附分子-A 缺失可增强小鼠脓毒症模型中的吞噬作用并提高生存率

Nathan J Klingensmith, Katherine T Fay, David A Swift, Julia Mr Bazzano, John D Lyons, Ching-Wen Chen, Mei Meng, Kimberly M Ramonell, Zhe Liang, Eileen M Burd, Charles A Parkos, Mandy L Ford, Craig M Coopersmith

TIGIT regulates apoptosis of risky memory T cell subsets implicated in belatacept-resistant rejection

TIGIT 调节与贝拉西普耐药排斥有关的危险记忆 T 细胞亚群的凋亡

He Sun, Christina R Hartigan, Ching-Wen Chen, Yini Sun, Marvi Tariq, Jennifer M Robertson, Scott M Krummey, Aneesh K Mehta, Mandy L Ford

TIGIT modulates sepsis-induced immune dysregulation in mice with preexisting malignancy

TIGIT 调节患有恶性肿瘤的小鼠中脓毒症引起的免疫失调

Wenxiao Zhang, Jerome C Anyalebechi, Kimberly M Ramonell, Ching-Wen Chen, Jianfeng Xie, Zhe Liang, Deena B Chihade, Shunsuke Otani, Craig M Coopersmith, Mandy L Ford

Membrane Permeant Inhibitor of Myosin Light Chain Kinase Worsens Survival in Murine Polymicrobial Sepsis

肌球蛋白轻链激酶的膜渗透性抑制剂使小鼠多重微生物脓毒症的生存率降低

Yini Sun, Takehiko Oami, Zhe Liang, Ashley A Miniet, Eileen M Burd, Mandy L Ford, Craig M Coopersmith