日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Intra-Individual Reproducibility of Automated Abdominal Organ Segmentation-Performance of TotalSegmentator Compared to Human Readers and an Independent nnU-Net Model

自动腹部器官分割的个体内部可重复性——TotalSegmentator 与人类读者和独立 nnU-Net 模型的性能比较

期刊:
影响因子:
doi:10.1007/s10278-024-01265-w
Abel, Lorraine; Wasserthal, Jakob; Meyer, Manfred T; Vosshenrich, Jan; Yang, Shan; Donners, Ricardo; Obmann, Markus; Boll, Daniel; Merkle, Elmar; Breit, Hanns-Christian; Segeroth, Martin
Human
发表日期：2025
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TotalSegmentator: Robust Segmentation of 104 Anatomic Structures in CT Images

TotalSegmentator：CT图像中104种解剖结构的稳健分割

期刊:Radiology-Artificial Intelligence
影响因子:13.2
doi:10.1148/ryai.230024
Wasserthal, Jakob; Breit, Hanns-Christian; Meyer, Manfred T; Pradella, Maurice; Hinck, Daniel; Sauter, Alexander W; Heye, Tobias; Boll, Daniel T; Cyriac, Joshy; Yang, Shan; Bach, Michael; Segeroth, Martin
发表日期：2023
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Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles

合理设计酶以实现生物催化鲍德温环化反应和手性杂环化合物的不对称合成

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-022-35468-y
Li, Jun-Kuan; Qu, Ge; Li, Xu; Tian, Yuchen; Cui, Chengsen; Zhang, Fa-Guang; Zhang, Wuyuan; Ma, Jun-An; Reetz, Manfred T; Sun, Zhoutong
发表日期：2022
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Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics

长程构象动力学对多种催化酶特性产生普遍的协同突变效应

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-021-21833-w
Acevedo-Rocha, Carlos G; Li, Aitao; D'Amore, Lorenzo; Hoebenreich, Sabrina; Sanchis, Joaquin; Lubrano, Paul; Ferla, Matteo P; Garcia-Borràs, Marc; Osuna, Sílvia; Reetz, Manfred T
发表日期：2021
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The Unexplored Importance of Fleeting Chiral Intermediates in Enzyme-Catalyzed Reactions

瞬时手性中间体在酶催化反应中尚未被充分发掘的重要性

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.1c04551
Reetz, Manfred T; Garcia-Borràs, Marc
发表日期：2021
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Machine Learning Enables Selection of Epistatic Enzyme Mutants for Stability Against Unfolding and Detrimental Aggregation

机器学习能够筛选出具有稳定性、抗展开和抗有害聚集能力的上位性酶突变体

期刊:Chembiochem
影响因子:2.8
doi:10.1002/cbic.202000612
Li, Guangyue; Qin, Youcai; Fontaine, Nicolas T; Ng Fuk Chong, Matthieu; Maria-Solano, Miguel A; Feixas, Ferran; Cadet, Xavier F; Pandjaitan, Rudy; Garcia-Borràs, Marc; Cadet, Frederic; Reetz, Manfred T
发表日期：2021
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Regio- and Stereoselective Steroid Hydroxylation at C7 by Cytochrome P450 Monooxygenase Mutants

细胞色素P450单加氧酶突变体对C7位甾体进行区域和立体选择性羟基化

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202003139
Li, Aitao; Acevedo-Rocha, Carlos G; D'Amore, Lorenzo; Chen, Jinfeng; Peng, Yaqin; Garcia-Borràs, Marc; Gao, Chenghua; Zhu, Jinmei; Rickerby, Harry; Osuna, Sílvia; Zhou, Jiahai; Reetz, Manfred T
细胞生物学
发表日期：2020
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Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution

实验室进化产生的具有高活性和改变的催化机制的人工半胱氨酸脂肪酶

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-019-11155-3.
Yixin Cen,Warispreet Singh,Mamatjan Arkin,Thomas S Moody,Meilan Huang,Jiahai Zhou,Qi Wu,Manfred T Reetz
发表日期：2019
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A machine learning approach for reliable prediction of amino acid interactions and its application in the directed evolution of enantioselective enzymes

一种用于可靠预测氨基酸相互作用的机器学习方法及其在对映选择性酶定向进化中的应用

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-018-35033-y
Cadet, Frédéric; Fontaine, Nicolas; Li, Guangyue; Sanchis, Joaquin; Ng Fuk Chong, Matthieu; Pandjaitan, Rudy; Vetrivel, Iyanar; Offmann, Bernard; Reetz, Manfred T
发表日期：2018
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Boosting the efficiency of site-saturation mutagenesis for a difficult-to-randomize gene by a two-step PCR strategy

通过两步 PCR 策略提高难以随机化的基因点饱和诱变效率

期刊:Applied Microbiology and Biotechnology
影响因子:3.9
doi:10.1007/s00253-018-9041-2
Aitao Li, Carlos G Acevedo-Rocha, Manfred T Reetz
信号转导
发表日期：2018
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