日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Correction to "From Discovery to Clinical Trial: YCT-529, an Oral NonHormonal Male Contraceptive Targeting the Retinoic Acid Receptor Alpha"

更正“从发现到临床试验:YCT-529,一种靶向视黄酸受体α的口服非激素男性避孕药”

Shi, Rui; Al Noman, Md Abdullah; Mannowetz, Nadja; Cheryala, Narsihmulu; Haque, Ehfazul; Taher, Noha; Maitra, Soma; Naqvi, Tahmina; Chung, Sanny S W; Bakshi, Akash; Hawkinson, Jon E; Wong, Henry L; Wolgemuth, Debra J; Georg, Gunda I

From Discovery to Clinical Trial: YCT-529, an Oral NonHormonal Male Contraceptive Targeting the Retinoic Acid Receptor Alpha

从发现到临床试验:YCT-529,一种靶向视黄酸受体α的口服非激素男性避孕药

Shi, Rui; Al Noman, Md Abdullah; Mannowetz, Nadja; Cheryala, Narsihmulu; Haque, Ehfazul; Maitra, Soma; Naqvi, Tahmina; Chung, Sanny S W; Bakshi, Akash; Hawkinson, Jon E; Wong, Henry L; Wolgemuth, Debra J; Georg, Gunda I

Safety and pharmacokinetics of the non-hormonal male contraceptive YCT-529

非激素男性避孕药YCT-529的安全性和药代动力学

Mannowetz, Nadja; McCallum, Stewart W; Sidhu, Sharan; Mena, Karen H; Ruby, Eric P; Castro-Santamaria, Ramiro; Dodds, Emily; Henderson, Dennis; Whitaker, Gareth; Wright, Heather; Beaudoin, Sarah; Bakshi, Akash

Targeting the retinoid signaling pathway with YCT-529 for effective and reversible oral contraception in mice and primates

利用YCT-529靶向类视黄醇信号通路,在小鼠和灵长类动物中实现有效且可逆的口服避孕

Mannowetz, Nadja; Chung, Sanny S W; Maitra, Soma; Noman, Md Abdullah Al; Wong, Henry L; Cheryala, Narsihmulu; Bakshi, Akash; Wolgemuth, Debra J; Georg, Gunda I

Dual Sensing of Physiologic pH and Calcium by EFCAB9 Regulates Sperm Motility

EFCAB9通过对生理pH值和钙离子的双重感知来调节精子活力

Jae Yeon Hwang ,Nadja Mannowetz ,Yongdeng Zhang ,Robert A Everley ,Steven P Gygi ,Joerg Bewersdorf ,Polina V Lishko ,Jean-Ju Chung

Single-cell Motility Analysis of Tethered Human Spermatozoa

人类精子的单细胞运动能力分析

William M Skinner, Nadja Mannowetz, Polina V Lishko, Nadia R Roan

Regulation of the sperm calcium channel CatSper by endogenous steroids and plant triterpenoids

内源性类固醇和植物三萜类化合物对精子钙通道CatSper的调控

Mannowetz, Nadja; Miller, Melissa R; Lishko, Polina V

Unconventional endocannabinoid signaling governs sperm activation via the sex hormone progesterone

非常规内源性大麻素信号通过性激素黄体酮控制精子激活

Melissa R Miller, Nadja Mannowetz, Anthony T Iavarone, Rojin Safavi, Elena O Gracheva, James F Smith, Rose Z Hill, Diana M Bautista, Yuriy Kirichok, Polina V Lishko

Normal Fertility Requires the Expression of Carbonic Anhydrases II and IV in Sperm

正常生育能力需要精子中碳酸酐酶 II 和 IV 的表达

Petra M Wandernoth, Nadja Mannowetz, Jaroslaw Szczyrba, Laura Grannemann, Anne Wolf, Holger M Becker, William S Sly, Gunther Wennemuth

Slo1 is the principal potassium channel of human spermatozoa

Slo1 是人类精子的主要钾通道

Nadja Mannowetz, Natasha M Naidoo, Seung-A Sara Choo, James F Smith, Polina V Lishko