日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Transcriptomic analysis of non-leukemic cell subsets in azacytidine-responsive AML highlights pathways associated with adhesion, platelet aggregation, and angiogenesis in mice and humans

对阿扎胞苷反应性急性髓系白血病(AML)中非白血病细胞亚群的转录组分析突显了小鼠和人类中与细胞黏附、血小板聚集和血管生成相关的通路。

Ebelt, Nancy D; Loganathan, Suvithanandhini; Avsharian, Lara C; Manuel, Edwin R

Intravital imaging reveals spatiotemporal dynamics of oncolytic Salmonella YB1-induced intratumoral vascular thrombosis and tumor targeting.

活体成像揭示了溶瘤沙门氏菌 YB1 诱导的肿瘤内血管血栓形成和肿瘤靶向的时空动态。

Yu Bin, Shi Lei, Duan Weiwang, Cui Dongmei, Manuel Edwin R, Huang Wei

Tumor-Colonizing E. coli Expressing Both Collagenase and Hyaluronidase Enhances Therapeutic Efficacy of Gemcitabine in Pancreatic Cancer Models

表达胶原酶和透明质酸酶的肿瘤定植大肠杆菌可增强吉西他滨在胰腺癌模型中的治疗效果

Avsharian, Lara C; Loganathan, Suvithanandhini; Ebelt, Nancy D; Shalamzari, Azadeh F; Rodarte Muñoz, Itzel; Manuel, Edwin R

Salmonella-mediated therapy targeting indoleamine 2, 3-dioxygenase 1 (IDO) activates innate immunity and mitigates colorectal cancer growth.

沙门氏菌介导的针对吲哚胺 2, 3-双加氧酶 1 (IDO) 的疗法可激活先天免疫并减轻结直肠癌的生长

Phan Thuy, Nguyen Vu H, D'Alincourt Marcela S, Manuel Edwin R, Kaltcheva Teodora, Tsai Weimin, Blazar Bruce R, Diamond Don J, Melstrom Laleh G

Targeting desmoplasia in pancreatic cancer as an essential first step to effective therapy

以胰腺癌间质增生为靶点是有效治疗的关键第一步

Ebelt, Nancy D; Zamloot, Vic; Manuel, Edwin R

Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Coupled with Enzymatic Depletion of Tumor Hyaluronan Induces Complete Regression of Aggressive Pancreatic Tumors

以沙门氏菌为基础,靶向吲哚胺2,3-双加氧酶,并结合酶促清除肿瘤透明质酸,可诱导侵袭性胰腺肿瘤完全消退。

Manuel, Edwin R; Chen, Jeremy; D'Apuzzo, Massimo; Lampa, Melanie G; Kaltcheva, Teodora I; Thompson, Curtis B; Ludwig, Thomas; Chung, Vincent; Diamond, Don J

A road less traveled paved by IDO silencing: Harnessing the antitumor activity of neutrophils

一条人迹罕至的道路:通过抑制IDO来发挥中性粒细胞的抗肿瘤活性

Manuel, Edwin R; Diamond, Don J

Survivin the battle against immunosuppression

在与免疫抑制的斗争中生存下来

Manuel, Edwin R; Blache, Céline A; Ellenhorn, Joshua D I; Diamond, Don J

Heterologous prime/boost immunization with p53-based vaccines combined with toll-like receptor stimulation enhances tumor regression

采用基于p53的疫苗进行异源初免/加强免疫,并结合Toll样受体刺激,可增强肿瘤消退。

Ishizaki, Hidenobu; Song, Guang-Yun; Srivastava, Tumul; Carroll, Kyla Driscoll; Shahabi, Vafa; Manuel, Edwin R; Diamond, Don J; Ellenhorn, Joshua D I